The Association of Extent of Axillary Surgery and Survival in Women with N2–3 Invasive Breast Cancer

Park, Tristen S; Thomas, Samantha M.; Rosenberger, Laura H.; Fayanju, Oluwadamilola M.; Plichta, Jennifer K.; Blitzblau, Rachel; Ong, Cecilia T.; Hyslop, Terry; Hwang, E. Shelley; Greenup, Rachel A.

doi:10.1245/s10434-018-6587-2

Cited by 20 publications

(9 citation statements)

References 24 publications

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“…When negative surgical margins can be achieved, breast conservative surgery is preferred over mastectomy [ 17 ]. Although the role of axillary dissection seems to diminish as standard procedure of breast cancer treatment and staging, it is indicated in cases with node-positive disease at diagnosis and axillary lymphadenectomy is associated with improved survival in patients presenting with clinical N2-3 invasive breast cancer [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Whole Breast Invasive Lobular Carcinoma Not Detected Radiographically

Vlastarakos

Marinopoulos

Dimopoulou

et al. 2020

Cureus

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Breast cancer is the most commonly occurring cancer in women, with invasive lobular carcinoma being the second most common histologic form. A 78-year-old female patient presented complaining of an enlarged palpable lymph node in the left axilla. Breast ultrasound, digital mammography, and contrast-enhanced spectral mammography (CESM) revealed no abnormal findings. Core needle biopsy of the lymph node revealed infiltrative, diffuse neoplastic growth suggestive of adenocarcinoma, indicating that the primary site should be sought in the breast. The patient underwent mastectomy and the histopathology was suggestive of invasive lobular carcinoma throughout the whole extent of the breast parenchyma. Breast cancer should be definitely included in the differential diagnosis of enlarged axillary lymph nodes, even if there is no other clinical or radiographic presentation of breast disease.

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Section: Discussionmentioning

confidence: 99%

Whole Breast Invasive Lobular Carcinoma Not Detected Radiographically

Vlastarakos

Marinopoulos

Dimopoulou

et al. 2020

Cureus

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“…They noted no statistical difference in OS between those receiving SLNB vs ALND 26 . On the other hand, Park et al evaluated women with cT1-3, cN2-3 disease (median age 56y) and noted an association between ALND and improved OS for patients with cN2 and cN3 disease 27 . This difference in the association between ALND and OS may be attributed to the size of the tumors in each study population: Bonneau et al examined patients with relatively small tumors (T1-2) compared to the study population of Park et al, which included T1-3 tumors.…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of the Axilla in Elderly Women With Node-Positive Breast Cancer

Marks

Ren

Rosenberger

et al. 2020

Journal of Surgical Research

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Background: Elderly women with clinically node-positive (cN+) breast cancer (BC) often have comorbidities that limit life expectancy and complicate treatment. We sought to determine whether the number of lymph nodes (LNs) retrieved among older women with node-positive breast cancer was associated with overall survival (OS).Methods: Using the National Cancer Database (2010Database ( -2015, women 70-90y with cN+ BC and ≥1 LN removed were categorized by treatment sequence: upfront surgery or neoadjuvant

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“… 14 , 15 Axillary lymphadenectomy was associated with improved survival in patients presenting with clinical N2–3 invasive breast cancer. 16 Most surgeons perform axillary lymph node dissection in patients with positive axillary lymph nodes. There are many reasons for this, such as difficulties in treating axillary recurrence, the psychological impact of recurrence in patients, and problems in a rigorous follow-up.…”

Section: Indications Of Level III Axillary Lymph Node Dissectionmentioning

confidence: 99%

Dissection of Level III Axillary Lymph Nodes in Breast Cancer

Hu¹,

Xia²,

Yang³

et al. 2021

CMAR

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Axillary lymph node dissection is an indispensable step in modified radical mastectomy for breast cancer. It is the most reliable method and the golden standard to determine the status of axillary lymph nodes. It is also of great importance to evaluate the prognosis and develop treatment plans for breast cancer patients. Axillary lymph node dissection can be anatomically divided into levels I, II, and III. Level I and Level II axillary lymph dissection is the standard clinical treatment of axillary lymph nodes positive breast cancer, whereas level III axillary lymph node dissection has been controversial. Level III axillary lymph node metastasis is one of the important factors that can easily cause distant metastasis and recurrence. It is also an important index to estimate the prognosis of breast cancer patients. To facilitate the decision of whether or not to perform level III lymph node dissection, we reviewed the indications, complications, and surgical procedures of level III lymph node dissection.

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The Association of Extent of Axillary Surgery and Survival in Women with N2–3 Invasive Breast Cancer

Cited by 20 publications

References 24 publications

Whole Breast Invasive Lobular Carcinoma Not Detected Radiographically

Whole Breast Invasive Lobular Carcinoma Not Detected Radiographically

Surgical Management of the Axilla in Elderly Women With Node-Positive Breast Cancer

Dissection of Level III Axillary Lymph Nodes in Breast Cancer

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