The Association of Dilated Cardiomyopathy with Essential Hypertension

Abstract

The objective of the study was to determine the association of DCMP and essential hypertension. We examined 1820 outpatients using echocardiography. Office blood pressure, height and weight were measured to all of them. 9 males and 1 female with dilated cardiomyopathy and essential hypertension and 11 males and 2 females with dilated cardiomyopathy but without hypertension were identified among these subjects. Control group consisted of 97 men with essential hypertension and no signs of dilated cardiomyopathy. Mean age in dilated cardiomyopathy group was 56.5 (5.5) and in dilated cardiomyopathy and essential hypertension-52.1 (3.6) years. Male to female ratio was 11:2 and 9:1 respectively for these groups. Based on cluster analysis we assumed that both groups belong to the same cluster. Using ANOVA statistically significant differences of body mass index and diastolic blood pressure were found between groups with dilated cardiomyopathy and essential hypertension and essential hypertension without dilated cardiomyopathy. Results of cluster analysis allowed us to suspect that there were no specific characters of dilated cardiomyopathy in hypertensive patients comparing with normotensives. At the same time hypertensive patients had higher risk of dilated cardiomyopathy if they were of male gender, aged 49-55, with the obesity and high diastolic pressure (over 100 mm Hg).

Synthesis of Hydrophobic Polymeric Cryogels with Supermacroporous Structure

“…Most of literature focused on synthesis and application of hydrophilic cryogels such as polyacrylamide‐ and polyvinyl alcohol‐based cryogels, where ice crystals were used as porogen templates . Only a few investigations involved hydrophobic cryogels . Lozinsky et al used polystyrene as precursor and xylylene dichloride as crosslinker in the medium of frozen nitrobenzene to obtain hydrophobic cryogels .…”

Supermacroporous polydivinylbenzene cryogels with high surface area: Synthesis by solvothermal postcrosslinking and their adsorption behaviors for carbon dioxide and aniline

“…Cryogels are a type of supermacroporous materials of interconnected micrometer‐scale porous structures obtained from crosslinking of monomeric or polymeric precursors via either covalent interactions, or noncovalent interactions, or ionic interactions at freezing temperatures below the melting point of the solvent and pore formation with solvent crystals . Compared to poly high internal phase emulsions (HIPEs), another class of supermacroporous materials, cryogels are “green” and easy of preparation mainly due to free of any surfactant .…”

Vesicle‐Like Globules of Amphiphilic Macromolecules

“…As a result, such globules are strongly protected from aggregation . These results are consistent with some of the existing experimental data …”

“…[6,7] These results are consistent with some of the existing experimental data. [11][12][13][14][15][16][17] To date, application of amphiphilic unit model allowed to reveal conditions necessary to obtain globules, soluble at high polymer concentrations; [6,7] propose a model of selforganization and fibrils formation in solvents of biological and biomimetic synthetic macromolecules; [6,18,19] suggest an effective technique to create nanocapsules, [20] to make ultra-thin surface layers, [21] and to design materials with specific crystalline-like ordering of solvent; [22] study of the structure of polyelectrolytes with pendant architecture in solutions. [23] In the present work, we continue to study macromolecules, which are amphiphilic on the level of an individual monomer unit, and investigate the conformation properties and intramolecular self-organization of a flexible A-graft-B macromolecule in selective solvent being now (contrary to our previous study) good for the backbone and poor for the side groups.…”