The association of body mass index variability with cardiovascular disease and mortality: a mediation analysis of pooled cohorts
Ladan Mehran,
Mohammadjavad Honarvar,
Safdar Masoumi
et al.
Abstract:AimWe aimed to investigate the effect of BMI variability on CVD and mortality and to explore the mediation effects of the main cardiovascular risk factors contributing to this association.MethodParticipants aged 40-65 years were pooled from three cohort studies(ARIC [Atherosclerosis Risk in Communities], MESA [Multi-ethnic Study of Atherosclerosis], and TLGS [Tehran Lipid and Glucose Study]. We employed root mean squared error of the fractional mixed model to calculate BMI variability in the measurement period… Show more
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