The Association of Adiponectin Serum Level and Body Mass Index among Javanese Obese Adolescents

Abstract

Introduction : The adiponectin level should decrease in obese people, however, many previous studies' results about its role in obesity still remain controversies. The present study aimed to evaluate the profile of adiponectin serum level among obese adolescents in Javanese population and its correlation with body mass index (BMI) Methods : A cross-sectional study involving obese adolescents aged 13-18 years old from some schools was conducted from May to September 2020. The subject were determined by using a total population sampling method that met inclusion and exclusion criteria. Anthropometries were measured to count BMI and determine obesity according to CDC 2000. The adiponectin serum level was examined by ELISA from blood samples. Data were analyzed using Mann-Whitney Test and Spearmann correlation, with a significance value at p < 0.05.Results: There were 240 obese adolescents involved (52.1% boys) in the present study. There were significant differences in the mean of body-weight and body-height according to gender (p<0.05), however, there was no significant difference in BMI based on genders. The median of adiponectin serum level was 13.9 (1.5-46.6) µg/ml, which had no correlation with BMI (p=0.98; r=0.002). Conclusion:The adiponectin serum level had no significant correlation to body mass index. More studies are suggested to find out several factors that might influence the adiponectin serum level in Javanese population.