The association between zinc and endothelial adhesion molecules ICAMs and VCAM-1 and nuclear receptors PPAR-ɑ and PPAR-γ: A systematic review on cell culture, animal and human studies

Gholizadeh, Mohammad; Saeedy, Said Abdul Ghafour; Roodi, Poorya Basafay; Saedisomeolia, Ahmad

doi:10.1016/j.mvr.2021.104217

Cited by 10 publications

(10 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, ROS activate endothelial markers by inducing E-selectin, sICAM-1 and sVCAM-1. It has been reported that sICAM-1 plays an important role as a predictor of CVD (Luc et al , 2003; Gholizadeh et al , 2021). Moreover, the sVCAM-1 expression represents the inflammatory conditions of the vascular walls and predicts fatal coronary artery disease in the future (Malik et al , 2001; Blankenberg et al , 2001).…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the sVCAM-1 expression represents the inflammatory conditions of the vascular walls and predicts fatal coronary artery disease in the future (Malik et al , 2001; Blankenberg et al , 2001). Plasma levels of endothelial markers such as sE-selectin and sICAM-1 correlate with prognosis (Tenaglia et al , 1997; Gholizadeh et al , 2021; Patel et al , 2020). Many studies have assessed the correlation between DIP and CVD.…”

Section: Discussionmentioning

confidence: 99%

“…b Body mass index !25. c High SES; socioeconomic status was defined based on income, educational level, family size, renting the house, being owner of the house or house area, being owner of the car and number of the cars and kind of the car(s), number of bedrooms and determination of who was in charge of the family Dietary inflammatory potential sE-selectin and sICAM-1 correlate with prognosis (Tenaglia et al, 1997;Gholizadeh et al, 2021;Patel et al, 2020). Many studies have assessed the correlation between DIP and CVD.…”

Section: Discussionmentioning

confidence: 99%

“…Endothelial dysfunction is characterized by impaired activity of endothelial derived relaxant factors and increased activity of vasoconstrictor factors. However, cell adhesion molecules (CAM) including E-selectin, intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) accelerate atherosclerosis (Ajjan and Grant, 2006; Kim et al , 2006; Davignon and Ganz, 2004; Libby et al , 2002; Gholizadeh et al , 2021).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Association of dietary inflammatory potential (DIP) and endothelial function biomarkers among females

Gholizadeh

Falahi

Keshteli

et al. 2022

NFS

Self Cite

View full text Add to dashboard Cite

Purpose Dietary inflammatory potential (DIP) is a novel dietary index designed to evaluate individuals’ diets with considering inflammation and anti-inflammation score. In addition, adhesion molecules including soluble intracellular adhesion molecules-1 (sICAM-1), soluble cellular adhesion molecules-1 (sVCAM-1) and E-selectin are important biomarkers to assess endothelium dysfunction which are related to atherosclerosis and cardiovascular complications. Also, there is no study for assessing the association between adhesion molecules and DIP until now as well as other studies that assessed the relationship between dietary inflammatory index or DIP has controversy. The purpose of this cross-sectional study was to determine the correlation between DIP and endothelial markers such as E-selectin, sICAM-1 and sVCAM-1 among female nurses from Isfahan. In this study, DIP was used instead of DII. Design/methodology/approach This study was performed on 420 healthy nurses. The nurses were selected by random cluster sampling method from private and public Isfahan hospitals. A validated food frequency questionnaire (FFQ) was applied to assess the DIP. A fasting blood sample was collected for measuring the plasma levels of the endothelial markers and other variables. Findings After adjusting different potential confounders, no statistical association was found between DIP and sICAM-1, E–selectin and sVCAM-1 in Model I (P = 0.57, 0.98 and 0.45), Model II (P = 0.57, 0.98 and 0.45) and Model III (P = 0.67, 0.92 and 0.50) in comparison to the crude group (P = 0.35, 0.83 and 0.49, respectively). Originality/value The results revealed that the plasma levels of endothelial markers including E-selectin, sICAM-1 and sVCAM-1 were not significantly associated with DIP in female nurses.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Association of dietary inflammatory potential (DIP) and endothelial function biomarkers among females

Gholizadeh

Falahi

Keshteli

et al. 2022

NFS

Self Cite

View full text Add to dashboard Cite

show abstract

“…Vascular cell adhesion molecule-1 (VCAM-1), an important cell adhesion molecule, triggers monocytes’ attachment to ECs and promotes the development of atherosclerotic plaques. Zinc deficiency increases the production of VCAM-1 and intercellular adhesion molecules (ICAM-1), thereby promoting inflammation [ 76 ]. Zinc additionally affects the expression of multiple pro-inflammatory cytokines in ECs.…”

Section: Zinc and Atherogenic Cellsmentioning

confidence: 99%

Investigating the Role of Zinc in Atherosclerosis: A Review

et al. 2022

View full text Add to dashboard Cite

Zinc, an indispensable micronutrient for human health, might play an important role in the development of atherosclerosis. Zinc could be involved in the atherogenic process through interaction with atherogenic cells, such as endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and immune cells. In addition, zinc also exerts important positive or negative functions in various atherosclerosis-related risk factors, including lipid metabolism, glucose metabolism, and blood pressure. Currently, evidence focusing on the relationship between zinc status and atherogenic risk factors has been well established, while the direct interaction between zinc and atherosclerosis has not been fully understood. In this review, we aimed to summarize the association between zinc and atherosclerosis and explore current findings on how zinc and zinc homeostasis-associated proteins act in the atherogenic processes.

show abstract

Critical appraisal tools used in systematic reviews of in vitro cell culture studies: A methodological study

Barbosa

Silveira

Santos

et al. 2023

Research Synthesis Methods

View full text Add to dashboard Cite

Systematic reviews (SRs) of preclinical studies are marked with poor methodological quality. In vitro studies lack assessment tools to improve the quality of preclinical research. This methodological study aimed to identify, collect, and analyze SRs based on cell culture studies to highlight the current appraisal tools utilized to support the development of a validated critical appraisal tool for cell culture in vitro research. SRs, scoping reviews, and meta‐analyses that included cell culture studies and used any type of critical appraisal tool were included. Electronic search, study selection, data collection and methodological quality (MQ) assessment tool were realized. Further, statistical analyses regarding possible associations and correlations between MQ and collected data were performed. After the screening process, 82 studies remained for subsequent analysis. A total of 32 different appraisal tools were identified. Approximately 60% of studies adopted pre‐structured tools not designed for cell culture studies. The most frequent instruments were SYRCLE (n = 14), OHAT (n = 9), Cochrane Collaboration's tool (n = 7), GRADE (n = 6), CONSORT (n = 5), and ToxRTool (n = 5). The studies were divided into subgroups to perform statistical analyses. A significant association (OR = 5.00, 95% CI = 1.54–16.20, p = 0.008) was found between low MQ and chronic degenerative disorders as topic of SR. Several challenges in collecting information from the included studies led to some modifications related to the previously registered protocol. These results may serve as a basis for further development of a critical appraisal tool for cell culture studies capable of capturing all the essential factors related to preclinical research, therefore enhancing the practice of evidence‐based.

show abstract

The association between zinc and endothelial adhesion molecules ICAMs and VCAM-1 and nuclear receptors PPAR-ɑ and PPAR-γ: A systematic review on cell culture, animal and human studies

Cited by 10 publications

References 54 publications

Association of dietary inflammatory potential (DIP) and endothelial function biomarkers among females

Association of dietary inflammatory potential (DIP) and endothelial function biomarkers among females

Investigating the Role of Zinc in Atherosclerosis: A Review

Critical appraisal tools used in systematic reviews of in vitro cell culture studies: A methodological study

Contact Info

Product

Resources

About