The Association between Transformation Ability and Antimicrobial Resistant Potential in <i>Haemophilus influenzae</i>
Emi Tanaka,
Takeaki Wajima,
Ruri Ota
et al.
Abstract:The prevalence of quinolone low-susceptible H. influenzae has increased in Japan. Low quinolone susceptibility is caused by point mutations in target genes; however, it can also be caused by horizontal gene transfer via natural transformation. In this study, we examined whether this horizontal gene transfer could be associated with resistance to not only quinolones but also other antimicrobial agents. Horizontal transfer ability was quantified using the experimental transfer assay method for low quinolone susc… Show more
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