The association between the serum level of vitamin D and ischemic heart disease: a study from Jordan

Jarrah, Mohamad; Mhaidat, Nizar M.; Alzoubi, Karem H.; Alrabadi, Nasr; Alsatari, Enas S.; Khader, Yousef; Bataineh, Malik

doi:10.2147/vhrm.s167024

Cited by 9 publications

(13 citation statements)

References 56 publications

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“…Of these patients, 133 were suffering from coronary artery stenosis. The study, however, did not show any association between vitamin D abnormalities and the incidence or the reoccurrence of coronary artery stenosis [3].…”

Section: Studies Addressing Vitamin D Deficiency and Coronary Artery contrasting

confidence: 61%

“…The possible association between vitamin D circulating levels and coronary heart disease was addressed also in other previous recent studies [3][4][5][6][7], however, the issue is intriguing and controversial.…”

Section: Introductionmentioning

confidence: 92%

“…In a clinical setting similar to that addressed by Raslan E et al [1], Jarrah MI et al [3] measured serum levels of vitamin D using radioimmunoassay in 186 Jordanian patients who underwent investigative coronary catheterization. Of these patients, 133 were suffering from coronary artery stenosis.…”

Section: Studies Addressing Vitamin D Deficiency and Coronary Artery mentioning

confidence: 99%

See 2 more Smart Citations

Vitamin D and Ischaemic Heart Disease: A Casual or A Causal Association?

Rizzoni

Nardin

2019

High Blood Press Cardiovasc Prev

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Section: Studies Addressing Vitamin D Deficiency and Coronary Artery contrasting

confidence: 61%

Section: Introductionmentioning

confidence: 92%

Section: Studies Addressing Vitamin D Deficiency and Coronary Artery mentioning

confidence: 99%

See 1 more Smart Citation

Vitamin D and Ischaemic Heart Disease: A Casual or A Causal Association?

Rizzoni

Nardin

2019

High Blood Press Cardiovasc Prev

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“…Variables which are well recognized as important predictors of either hypertension risks or As intake should be considered when testing the association between E-iAs ing,rice and hypertension risks (Banda et al 2010;Biino et al 2013;Chen et al 2007;Jarrah et al 2018;Kim and Lee 2019;Lelong et al 2019;Mohtasham-Amiri et al 2018;Re 2009). In general, confounding information in the present study (Sex (gender), age (age of respondent 16 ?…”

Section: Definition Of Confoundersmentioning

confidence: 99%

Exploratory study of the association in the United Kingdom between hypertension and inorganic arsenic (iAs) intake from rice and rice products

Polya

2020

Environ Geochem Health

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Hypertension risks arising from chronic exposure to inorganic arsenic (iAs) are well documented. Consumption of rice is a major iAs exposure route for over 3 billion people; however, there is a lack of epidemiological evidence demonstrating an association of hypertension risks with iAs intake from rice, especially in areas where there is little exposure from drinking water but a growing demand for rice intake. To address this, we conducted an individual-level cross-sectional analysis to quantify the extent to which daily iAs intake from rice and rice products (E-iAs ing,rice ) modifies the association between hypertension risks and previously well-established risk factors. The analysis was based on secondary dietary, sociodemographic and health status data of 598 participants recorded in the UK National Diet and Nutrition Survey 2014-2016. E-iAs ing,rice and five blood pressure endpoints were derived with potential associations explored through generalized linear models. According to the results, a negative but not significant relationship was found between hypertension risks and E-iAs ing,rice after adjusting for major risk factors, notably age, gender, diabetes and obesity, with relatively higher risks being observed for male, middle-aged, overweight, alcohol consumer or Asian or Asian British, Black or Black British and mixed ethnic groups. Though inconclusive and mainly limited by potential incomplete adjustment for major confounders and intrinsic disadvantages of a crosssectional design, this study was the first quantifying the individual level dose-response relationship between E-iAs ing,rice and hypertension risks and is consistent with previous studies on the limited associations of hypertension with low-level arsenic exposure from drinking water. Larger scale cohort studies are indicated to quantify the association but in any event it is likely to be weak.

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“…13 Also, Jarrah et al did not find any association between vitamin D deficiency and the incidence or the reoccurrence of coronary artery stenosis. 14 So, the relationship between vitamin D status and CAD is still a matter of ongoing debate, and this merits further investigation. In Bangladesh, both hypovitaminosis D and CAD are common, and an association may exist between these two public health problems, i.e., hypovitaminosis D and CAD.…”

mentioning

confidence: 99%

Vitamin D Status and Acute Coronary Syndrome – A Single-Centre Study

Rahman¹,

Mm²,

Islam³

et al. 2021

Cardiovasc. j.

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Background: Vitamin D are needed for normal functioning of cardiovascular system, and its deficiency has been linked to different cardiovascular disorders, including hypertension. However, the relationship between vitamin D deficiency and ischaemic heart disease is not yet clear. The present study was intended to find out the association between serum vitamin D level and acute coronary syndrome (ACS). Methods: The cross-sectional analytical study was carried out in a tertiary care hospital of Dhaka, Bangladesh. Fifty-one consecutive ACS patients admitted into the Department of Cardiology of the hospital were considered as the cases and 51 apparently healthy subjects were considered as the controls. The exposure and outcome variables were serum vitamin D and ACS respectively. Vitamin D insufficiency and deficiency were defined as serum 25(OH) D <30-20 ng/ml and <20 ng/ml, respectively. Severe vitamin D deficiency was defined as serum 25(OH) D <10 ng/ml. Results: Hypovitaminosis D was prevalent in both cases and controls; however, the mean serum 25(OH) D was significantly lower in the former than the latter (14.2 ± 5.9 ng/ml vs. 18.2 ± 6.3 ng/ ml, respectively; p <0.001). Vitamin D insufficiency and moderate deficiency (serum 25(OH) D <20- 10 ng/ml) did not differ significantly between the groups, but severe deficiency (<10 ng/ml) was significantly more common in patients with ACS compared to the healthy controls. The risk of having moderate and severe vitamin D deficiency was 1.9-fold (95% CI = 0.8 – 4.7) and 22.8-fold (2.9 – 180.4) higher for ACS patients than for healthy subjects (p = 0.173 and p <0.001, respectively). Conclusion: Vitamin D deficiency is more common in patients with ACS compared to those without ACS. However, the independent association between vitamin D deficiency and ACS needs further evaluation. Cardiovasc. j. 2021; 13(2): 183-188

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The association between the serum level of vitamin D and ischemic heart disease: a study from Jordan

Cited by 9 publications

References 56 publications

Vitamin D and Ischaemic Heart Disease: A Casual or A Causal Association?

Vitamin D and Ischaemic Heart Disease: A Casual or A Causal Association?

Exploratory study of the association in the United Kingdom between hypertension and inorganic arsenic (iAs) intake from rice and rice products

Vitamin D Status and Acute Coronary Syndrome – A Single-Centre Study

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