The Association Between the Cardio-ankle Vascular Index and Other Parameters of Vascular Structure and Function in Caucasian Adults: MARK Study

Gómez‐Sánchez, Leticia; García‐Ortiz, Luis; Patino-Alonso, María C.; Recio-Rodríguez, José I; Frontera, Guillermo; Ramos, Rafel; Martí, Ruth; Agudo‐Conde, Cristina; Rodríguez‐Sánchez, Emiliano; Maderuelo‐Fernández, José Ángel; Gómez‐Marcos, Manuel A.

doi:10.5551/jat.28035

Cited by 42 publications

(33 citation statements)

References 44 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Bland -Altman plots, the mean difference of the two measurements was 0.2, and the 95% limits of agreement (mean 1.96 SD) was 1.2 and 1.7 10) . CAVI is also known to be associated with traditional parameters of vascular structure and function, such as intimamedia thickness (IMT), pulse wave velocity (PWV), and central augmentation index 11) . Furthermore, no special technique is required for the measurement of CAVI.…”

Section: Measurement Of Cavimentioning

confidence: 99%

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders

Sato

Nagayama

Saiki

et al. 2016

JAT

View full text Add to dashboard Cite

show abstract

Section: Measurement Of Cavimentioning

confidence: 99%

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders

Sato

Nagayama

Saiki

et al. 2016

JAT

View full text Add to dashboard Cite

show abstract

“…There are several studies reporting the relationship between CAVI and carotid arteriosclerosis observed using ultrasonography 19,21,22,32,33) . In summary, the abovementioned results indicated that CAVI could be a good maker of the progression of arteriosclerosis.…”

Section: (D) Carotid Arteriosclerosismentioning

confidence: 99%

The Role of a Novel Arterial Stiffness Parameter, Cardio-Ankle Vascular Index (CAVI), as a Surrogate Marker for Cardiovascular Diseases

Saiki

Sato

Watanabe

et al. 2016

JAT

View full text Add to dashboard Cite

Measurement of arterial stiffness in routine medical practice is important to assess the progression of arteriosclerosis. So far, many parameters have been proposed to quantitatively represent arterial stiffness. Among these, pulse wave velocity (PWV) has been most frequently applied to clinical medicine because those could be measured simply and non-invasively. PWV had established the usefulness of measuring arterial wall stiffness. However, PWV essentially depends on blood pressure at the time of measurement. Therefore, PWV is not appropriate as a parameter for the evaluation of arterial stiffness, particularly for the studies involving blood pressure changes.On the other hand, stiffness parameter is an index reflecting arterial stiffness without the influence of blood pressure. Recently, this parameter has been applied to develop a new arterial stiffness index called cardio-ankle vascular index (CAVI). Therefore, CAVI does not depend on blood pressure changes during the measurements; CAVI could represent the stiffness of the arterial tree from the origin of the aorta to the ankle.Many clinical studies obtained from CAVI are being accumulated. CAVI showed high value in arteriosclerotic diseases, such as coronary artery diseases, cerebral infarction, and chronic kidney diseases, and also in majority of people with various coronary risk factors. The improvement of those risk factors decreased CAVI. Furthermore, the role of CAVI as a predictor of cardio-vascular events was reported recently.We review the clinical studies on CAVI and discuss the clinical usefulness of CAVI as a candidate surrogate end-point marker for cardiovascular disease.

show abstract

“…Arterial stiffness (AS) is defined by a reduction in arterial compliance, which has been associated with cardiovascular events and atherosclerotic disease in several reports [1][2][3][4][5] . Clinically, the most representative and noninvasive technique for assessing AS is pulse wave velocity (PWV) measurement 6) .…”

Section: Introductionmentioning

confidence: 99%

A New Method for Cerebral Arterial Stiffness by Measuring Pulse Wave Velocity Using Transcranial Doppler

Huang

Wong

et al. 2016

JAT

View full text Add to dashboard Cite

Xian Fu and Chuming Huang contributed equally to this work Aim: Pulse wave velocity (PWV) has been regarded as the "gold standard" measurement of arterial stiffness (AS), but it is still only used in the assessment of central and peripheral arteries. We constructed a new method to evaluate cerebral AS by measuring PWV using transcranial Doppler (TCD). Methods: In all, 90 healthy subjects who received annual health screening were consecutively enrolled in this study between January 2011 and June 2013. Data on clinical characteristics, brachium-ankle (ba) PWV, and carotid-cerebral (cc) PWV measured with our newly constructed method by two experienced operators were recorded. cc PWV was calculated as the distance between two points in the common carotid artery and proximal part of ipsilateral middle cerebral artery, which was divided by the pulse transit time between these two points where the pulse was measured using TCD. Results: The value of cc PWV was 499.3 78.6 cm/s. Correlation between cc PWV and ba PWV in the assessment of AS was r 0.794 (P 0.001). The concordance between both the above mentioned methods was good. Interobserver and intraobserver reliability using interclass correlation for measuring cc PWV were 0.815 (P 0.001) and 0.939 (P 0.001), respectively. In multivariable analysis, older age ( 4.51, P 0.001) and increased diastolic blood pressure ( 2.39, P 0.001) were independently associated with higher cc PWV. Conclusion: cc PWV measured using TCD may be a promising method for the assessment of human cerebral AS, which is independently associated with age and diastolic blood pressure.

show abstract

The Association Between the Cardio-ankle Vascular Index and Other Parameters of Vascular Structure and Function in Caucasian Adults: MARK Study

Cited by 42 publications

References 44 publications

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders

The Role of a Novel Arterial Stiffness Parameter, Cardio-Ankle Vascular Index (CAVI), as a Surrogate Marker for Cardiovascular Diseases

A New Method for Cerebral Arterial Stiffness by Measuring Pulse Wave Velocity Using Transcranial Doppler

Contact Info

Product

Resources

About