Importance: Women undergoing cerclage placement remain at high risk for preterm labor and preterm prelabor rupture of membranes (PPROMs). The management of cervical cerclage after PPROM is controversial given the potential for prolonged latency when the cerclage is kept in place balanced with a potential increased risk of maternal infectious morbidity.Objective: In this review, we compared studies that examined maternal, fetal, and neonatal outcomes in women with cerclage at the time of PPROM. We evaluated latency after PPROM and maternal and neonatal complications in the setting of PPROM with cervical cerclage.Evidence Acquisition: Original research articles, review articles, and guidelines on cerclage removal were reviewed.Results: Nine studies comparing cerclage retention versus removal were examined with mixed results, in particular between studies before the routine use of latency antibiotics and corticosteroid administration. There was an associated increase in latency to delivery with retention of cerclage, with a potential increase in maternal infectious morbidity. No significant differences were noted for neonatal mortality, neonatal sepsis, or other neonatal morbidity outcomes. The majority of studies were limited by their retrospective nature and small sample sizes.Conclusions and Relevance: Cerclage removal at the time of diagnosis of PPROM can be considered due to the concern for increased risk of maternal morbidity without definitive benefit in latency to delivery or neonatal outcomes. However, data are limited, and clinicians should engage in shared decision-making with patients in this setting.Target Audience: Obstetricians and gynecologists, pediatricians Learning Objectives: After participating in this activity, the provider should be better able to summarize the current evidence regarding maternal, obstetric, and neonatal outcomes for women with PPROM in the setting of cervical cerclage; describe clinical evaluation for women who present with cerclage at the time of PPROM; and evaluate management considerations for women who present with cerclage at the time of PPROM.Cervical cerclage is a valuable intervention performed in the second trimester of pregnancy for women with suspected cervical insufficiency. 1 Cerclage placement has been shown to reduce the risk of preterm birth and pregnancy loss, as well as the risk of perinatal death. 1,2 However, women undergoing cerclage placement remain at high risk for preterm labor and preterm prelabor rupture of membranes (PPROMs). Although cerclage does not seem to increase the risk of PPROM compared with other women at increased risk of preterm birth, there is an association between cerclage placement and PPROM likely due to underlying risk factors. 3 PPROM is strongly associated with maternal, fetal, and neonatal morbidity and mortality due to increased risk of infection, oligohydramnios,