The association between referral by specialists in oral diagnosis on survival rates of patients with oral cancer: A retrospective cohort study

Abstract

BackgroundTo assess the influence of diagnosis and referral provided by specialists in oral diagnosis on disease‐free survival and overall survival of patients with oral cancer.MethodsA cohort of 282 patients with oral cancer treated at a regional cancer hospital from 1998 to 2016 was analyzed retrospectively. The referral register of the patients was analyzed and assigned to two groups: (1) those referred by oral diagnosis specialists (n = 129), or (2) those referred by nonspecialized professionals (n = 153). The cancer treatment evolution was assessed from the patients' records, and the outcome was registered concerning cancer recurrence and death. Sociodemographic and clinicopathological variables were explored as predictors of disease‐free survival and overall survival.ResultsGroup 1 exhibited lower T stages and a reduced incidence of regional and distant metastases. Surgery was performed in 75.2% of cases in Group 1, while in Group 2, the rate was 60.8%. Advanced T stages and regional metastases reduced the feasibility of surgery. Higher TNM stages and tumor recurrence were associated with decreased disease‐free survival, while surgical intervention was a protective factor. Higher TNM stage had a negative impact on the overall survival.ConclusionSpecialized oral diagnosis did not directly impact disease‐free survival and overall survival and did not influence the indication of surgery in oral cancer; however, it was associated with the diagnosis of early tumors and better prognosis.