The association between platelet to lymphocyte ratio and left atrial appendage thrombogenic milieu in patients with non-valvular atrial fibrillation

Tek, Mujgan; Efe, Fatma Kaplan

doi:10.5505/amj.2022.89896

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2023

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“…Previous studies have shown that both the PLR and NLR are independent predictors of LAA thrombus in non-valvular AF (ref. 8,33 ). There is as yet no evidence that SII, which consists of PLR and NLR, predicts LAA thrombus although it has been found to be associated with thrombotic events in patients with acute coronary syndrome or malignancy [10][11][12] .…”

Section: Discussionmentioning

confidence: 99%

The predictive value of the systemic immune-inflammatory index for left atrial appendage thrombus in non-valvular atrial fibrillation

Koca¹,

Levent²,

Şensoy³

et al. 2023

BIOMED PAP

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Objective. The systemic immune inflammatory index (SII) has prognostic value in cardiovascular diseases. The aim of current study was to investigate whether or not left atrial appendage (LAA) thrombus could be predicted by SII in patients with non-valvular atrial fibrillation. Method. The study included 525 patients newly diagnosed with non-valvular atrial fibrillation, who had not previously had anticoagulant treatment (50.7% male, mean age 62.94±10.79 years). All patients underwent transoesophageal echocardiography. Results. LAA thrombus was observed in 86 patients (16.4%). In the ROC curve SII had a good diagnostic power in predicting LAA thrombus (AUC: 0.760, 95% CI: 0.703-0.818, P<0.001). In the multivariate regression analysis, diabetes (

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