The association between oxidative balance score and periodontitis in adults: a population-based study

Abstract

IntroductionThe pathogenesis between oxidative stress and periodontitis was correlated. The Oxidative Balance Score (OBS) is a systematic tool to assess the effects of diet and lifestyle in relation to oxidative stress. However, the association between OBS and periodontitis has not been reported previously.MethodsSixteen dietary factors and four lifestyle factors were selected to score the OBS. Multivariate logistic regression and sensitivity analysis were used to investigate the relationship between OBS and periodontitis based on data from the National Health and Nutrition Examination Survey (NHANES) 1999–2018. Subgroup analysis and interaction tests were used to investigate whether this association was stable across populations.ResultsThis study included 3,706 participants. There was a negative linear association between OBS and periodontitis in all participants [0.89 (0.80, 0.97)], and after converting OBS to a quartile variable, participants with OBS in the highest quartile had a 29% lower risk of periodontitis than those with OBS in the lowest quartile [0.71 (0.42, 0.98)]. This negative association differed with respect to age and diabetes.ConclusionThere is a negative association between OBS and periodontitis in US adults. Our results suggest that OBS may be used as a biomarker for measuring periodontitis.

Association between oxidative balance score and rheumatoid arthritis in female: a cross-sectional study

“…Liu et al [44] found that TOBS and DOBS levels were positively correlated with vascular endothelial function, revealing another link between OBS and cardiovascular disease. Qu et al [45] illustrated a negative linear association between OBS and periodontitis among US adults, and the risk of periodontitis was reduced by 11% for every 1 unit increase in OBS, proposing OBS as a viable biomarker for periodontitis evaluation. The accruing body of evidence underscores the potential of OBS in evaluating a gamut of diseases, laying a robust foundation for our trailblazing study aimed at elucidating the relationship between OBS and RA.…”

Dietary and lifestyle oxidative balance scores are independently and jointly associated with nonalcoholic fatty liver disease: a 20 years nationally representative cross-sectional study

“…The OBS is a tool used to assess overall redox homeostasis in individuals and has been shown to be associated with colorectal cancer, CVD, and chronic kidney disease in previous epidemiological studies ( 33 ). More recent studies using NHANES have suggested that higher OBS is associated with improved cognitive function and depressive symptoms, and reduced risk of periodontitis and diabetes compared with those with the lowest OBS ( 7 , 8 , 34 , 35 ). After adjustment for all included confounders, OBS treated as both a continuous and a categorical variable, was associated with the risk of NAFLD but not AHF.…”

Association between oxidative balance score and self-reported severe headache or migraine based on NHANES 1999 to 2004 data: A cross-sectional study

“…A broad range of covariates was carefully evaluated, guided by existing literature [ [16] , [17] , [18] , [19] , [20] ]. These included demographic variables such as age, race/ethnicity, gender, educational attainment, marital status, poverty-to-income ratio (PIR), and total energy intake (kcal) [ 19 ].…”

“…Generally, a higher OBS indicates a dominance of antioxidants over pro-oxidants. Numerous studies have established a negative correlation between OBS and the prevalence of various diseases, such as leukocyte telomere length [ 15 ], diabetes mellitus [ 14 ], osteoarthritis [ 16 ], and periodontitis [ 17 ]. However, research exploring the potential link between OBS and migraine is notably limited.…”