The Association between Oral Health and Atherosclerotic Coronary Artery Disease in Patients submitted to Coronary Angiography: a Controlled Cross-Sectional Study

Oral health status and associated lifestyle behaviors in a sample of Iranian adults: an exploratory household survey

“…Current evidences show that poor oral hygiene is cause of biofilm accumulation and that relatively specific group of indigenous oral bacteria is cause of plaque-induced inflammatory periodontal diseases [1]. Poor oral health can result in additional complications, included swallowing, chewing, and speech difficulties, and these, in turn, can affect sleep quality and work productivity [2,3].…”

Relação entre Periodontite, Polimorfismos Genéticos e Doença Arterial Coronariana no Sul do Brasil

“…Periodontitis is a chronic, multifactorial inflammatory disease, resulting from a series of dysbiosis processes, activating the production of proteins and proinflammatory cytokines and signaling processes, thus, according to recent epidemiological, interventional and functional studies, establishing a causal association with the development of coronary artery disease. [10][11][12]16 The dichotomized age over 60 years and the male gender were also statistically associated with a higher probability of presenting CAD. It is noteworthy that age and male gender are already known risk factors for coronary artery disease and periodontitis, 23 so much so that many studies adjust for these factors only when analyzing atherosclerosis.…”

“…1,2,4,[10][11][12][13][14] Based on the inflammatory and immunological theories, several studies have been conducted aiming to establish this association through the genetic factor, the presence of polymorphisms in the genes that express the production of these factors and are associated to periodontitis, such as C-Reactive Protein (CRP) and interleukin-6 (IL-6). [15][16][17][18][19] The simple nucleotide polymorphism (SNP) of the IL-6 promoter gene may affect the production and expression of this cytokine; consequently, this change in serum levels may result in a relevant biological response. 18 The association between the SNP variant -174 G > C (rs1800795) and the increased risk of inflammatory diseases such as CAD has been previously demonstrated.…”

Oral health status and associated lifestyle behaviors among Iranian adults: a population based household survey

“…An association exists between poor oral health and cardiovascular disease, cancer, and respiratory diseases among human population [2,3]. Strong evidences indicated that untreated oral diseases and disorders not only negatively impact on general health, but they also increase the probability of diabetes and cardiovascular disease [4,5].…”