The association between obesity, hypertension and left ventricular mass in adolescents

Dibeklioğlu, Saime Ergen; Çevik, Berna Şaylan; Acar, Banu; Özçakar, Z. Bı̇rsı̇n; Uncu, Nermin; Kara, Nazlı; Çayci, Şemsa; Çakar, Nilgün

doi:10.1515/jpem-2016-0170

Cited by 13 publications

(6 citation statements)

References 11 publications

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“…Previous studies utilizing ABPM in obese children have shown the prevalence of ambulatory hypertension ranging from 20% to as high as 60% (5,6,17). The severity of hypertension increased with an increasing BMI in the present study, which is in concordance with previous studies.…”

Section: Discussionsupporting

confidence: 93%

“…Obese children with ABPM have shown a prevalence for ambulatory hypertension ranging from 25% to as high as 48.6% in previous studies (5,6) with 20% having severe ambulatory hypertension. It has been postulated previously that ambulatory systolic blood pressure and obesity are independently associated with left ventricular hypertrophic remodeling in children (7).…”

Section: Introductionmentioning

confidence: 90%

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Predictive Model for Ambulatory Hypertension Based on Office Blood Pressure in Obese Children

et al. 2020

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Background: The epidemic of obesity, along with hypertension (HT) and cardiovascular disease, is a growing contributor to global disease burden. It is postulated that obese children are predisposed to hypertension and subsequent cardiovascular disease in adulthood. Early detection and management of hypertension in these children can significantly modify the course of the disease. However, there is a paucity of studies for the characterization of blood pressure in obese children through ambulatory blood pressure monitoring (ABPM), especially in the developing world. This study aims to characterize ambulatory blood pressure in obese children and to explore feasibility of using office BP that will predict ambulatory hypertension. Methods: In the present study, 55 children with a body mass index (BMI) in the ≥95th percentile for age and sex were enrolled in a tertiary care hospital and underwent 24 h of ABPM and detailed biochemical investigations.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 90%

Predictive Model for Ambulatory Hypertension Based on Office Blood Pressure in Obese Children

et al. 2020

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“…There are not much well-established data for the correlation of LVMI with obese and hypertensive children yet. Dibeklioglu et al [40] reported that the most predictive values associated with LVMI in obese adolescents are 24-h mean SBP, and 24-h SBP load, daytime SBP load, nighttime SBP load and 24-h SBP, similar to our results. However, in normal weight-hypertensive adolescents, 24-h mean DBP, daytime diastolic load, daytime DBP index, daytime SBP index, nighttime systolic loading and nighttime DBP index were found to be predictors of the LVMI.…”

Section: Discussionsupporting

confidence: 92%

Effects of ambulatory blood pressure monitoring parameters on left ventricular mass index in hypertensive children

Soyaltın

Demir

Erfidan

et al. 2022

Blood Pressure Monitoring

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Objective We aimed to evaluate the effects of blood pressure (BP) values obtained by 24-h ambulatory BP monitoring (ABPM) of hypertensive children and adolescents on left ventricular mass index (LVMI). Methods Patients diagnosed with HT with BP measurements confirmed with ABPM and evaluated with echocardiography for LVMI were included. The patients were divided into two groups according to their BMI as obese and nonobese. SDSs of ABPM parameters were compared between the groups. Results A total of 158 children with HT were included in the study. Ninety of these patients were obese. In obese and nonobese cases, mean SDS levels were similar in ABPM parameters, whereas LVMI was significantly higher in obese patients (P = 0.049). There was a significant correlation between LVMI and 24-h SBP SDS, daytime SBP SDS, 24-h SBP load and daytime BP load. In obese cases, there was a statistically significant correlation between LVMI and 24-h SBP SDS, daytime SBP SDS, 24-h SBP load, daytime SBP load as well as nighttime SBP SDS and nighttime SBP load. When the whole group was evaluated, 24-h SBP SDS was the most effective parameter influencing LVMI (P = 0.001). Similarly, the most effective ABPM parameter on LVMI in obese patients was 24-h SBP SDS (P = 0.001). Conclusion A significantly higher rate of LVMI in obese patients suggests that obesity itself is an effective factor on LVMI. In addition, systolic hypertension is more effective on cardiac functions compared with DBP measurements and systolic-DBP dipping ratios.

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“…In research by Huang et al [5], obese patients had larger LAD, LAA, and LAV, both in univariate and multivariate analysis. Dibeklioglu et al [19] showed that obesity in children was a risk factor for LV hypertrophy independent of hypertension, and Kurisu et al [20] found an influence of BMI on the correlations between LVM and ECG indices used in the diagnosis of LV hypertrophy, such as the Cornell product and Sokolow-Lyon indices.…”

Section: Discussionmentioning

confidence: 99%

Relation between parameters of body composition and echocardiography in patients with nonvalvular atrial fibrillation

Anaszewicz

Budzyński²

2020

Medical Research Journal

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Purpose: Both nutritional status and echocardiographic parameters are associated with the risk of atrial fibrillation (AF). The aim of this study was to determine the relationships between parameters of transthoracic echocardiography and nutritional status assessment as risk factors for AF. Methods: This cross-sectional study considered 120 consecutive patients hospitalized due to AF and 240 inpatients admitted due to exacerbation of cardiovascular conditions. Echocardiographic parameters and parameters of nutritional status were determined for each patient. Results: Patients in the lowest body mass index (BMI) quartile and without visceral adiposity had the lowest standard echocardiographic parameters; however, the majority of these differences disappeared after the parameters were indexed to BSA. In logistic regression analysis, echocardiographic parameters were associated with slightly higher or similar AF risk comparing with parameters of nutritional status assessment. When the comparison was made in relation to cutoff values obtained in ROC analysis, then having a visceral adipose tissue (VAT) score ≥ 12 was associated with a lower increase in AF risk (odds ratio [OR]; 95% confidence interval [CI]: 3.09; 1.85-5.15) than the risk increase associated with e.g. left atrium diameter greater than 45mm ([OR; 95% CI] 10.483; 6.308-17.421). Conclusions: The unitary values of echocardiographic and body composition parameters only slightly differed in relation to the risk of AF occurrence, however, the use of cutoff values significantly increases an impact of echocardiography on the prediction of AF. The U-shaped relationships between a patient's nutritional status and AF occurrence cannot be explained by the effect of body mass on cardiac structure and size.

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The association between obesity, hypertension and left ventricular mass in adolescents

Cited by 13 publications

References 11 publications

Predictive Model for Ambulatory Hypertension Based on Office Blood Pressure in Obese Children

Predictive Model for Ambulatory Hypertension Based on Office Blood Pressure in Obese Children

Effects of ambulatory blood pressure monitoring parameters on left ventricular mass index in hypertensive children

Relation between parameters of body composition and echocardiography in patients with nonvalvular atrial fibrillation

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