“…Classical clinical and epidemiological studies unequivocally demonstrate that stress, allostatic load, low socioeconomic status (SES), and low social rank confer increased vulnerability to morbidity significantly shortening lifespan in humans (Chetty et al., 2016; Marmot et al., 1991; Seeman, Singer, Rowe, Horwitz & McEwen, 1997; Stringhini et al., 2012). Notably, a recent multicohort study of 1.7 million adults followed up for mortality (Stringhini et al., 2017) has recognized the effect of SES among other recognized WHO risk factors (i.e., smoking, obesity, diabetes, hypertension, alcohol intake) assigning it a notable 1.26 hazard ratio.…”