The association between hearing threshold and urinary personal care and consumer product metabolites in middle-aged and elderly people from the USA

Fu, Yanpeng; Chen, Wenyu; Guo, Liqing; Zhu, Yaqiong; Yuan, JiaSheng; Liu, Yuehui

doi:10.1007/s11356-022-21459-5

Cited by 2 publications

(1 citation statement)

References 38 publications

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“…A representative sample of non-institutional US populations is selected through a complex strati ed multi-stage sampling design. The NHANES programme was approved by the Ethical Review Board of the National Center for Health Statistics of the CDC, and written informed consent was provided to all participants during the survey (11,12). In the three cycles of 2005-2010, 10,537, 10,149 and 10,348 people participated in the NHANES program, a total of 31,034 people was shown in Fig.…”

Section: Study Pupulationmentioning

confidence: 99%

Association of bone mineral density and osteoporosis with trichlorophenol: A national-representative, population-based study

Yan

Xiong

Tao

et al. 2022

Preprint

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Background: Trichlorophenols (TCPs) are metabolites of several organochlorine chemicals, including chlorobenzene, hexachlorocyclohexane, and chlorophenoxy acid, present in air, surface water, soil, and sediment. However, the relationship between TCP and bone mineral density (BMD) and osteoporosis has not been studied yet. Methods: We used data from the 2005-2010 National Health and Nutrition Examination Survey (NHANES). TCP were obtained from urine specimens of 3385 participants and bone mineral density was obtained by dual X-ray absorptiometry (DXA) whole-body scanning. Multiple regression analysis, stratified analysis, curve fitting analysis, and trend tests were used to assess the relationship between TCP and BMD and osteoporosis. Result: After adjusting for confounding factors, the results of multiple regression analysis only showed that ln-2,4,5-TCP was negatively associated with BMD of lumbar spine. In stratified analyses, ln-2,4,5-TCP and ln-2,4,6-TCP was were not statistically associated with BMD in total femur, femoral neck, femoral tuberosity, intertrochanteric femur and lumbar spine, which was also confirmed by curve fitting analyses and trend tests. Multiple regression analysis and stratified analysis showed that ln-2,4,5-TCP and ln-2,4,6-TCP was were not statistically associated with osteopenia/osteoporosis. Conclusion: 2,4,5-TCP and 2,4,6-TCP were not significantly associated with BMD and osteopenia/osteoporosis in the US population.

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Section: Study Pupulationmentioning

confidence: 99%

Association of bone mineral density and osteoporosis with trichlorophenol: A national-representative, population-based study

Yan

Xiong

Tao

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

Association of bone mineral density with trichlorophenol: a population-based study

Yan

Xiong

Tao

et al. 2023

BMC Musculoskelet Disord

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Background Trichlorophenols (TCPs) are metabolites of several organochlorine chemicals, including chlorobenzene, hexachlorocyclohexane, and chlorophenoxy acid, present in air, surface water, soil, and sediment. Many studies have shown that endocrine disruptors (EDs)may contribute to decreased bone mass and the increased risk of osteoporosis. However, the relationship between TCP and bone mineral density (BMD) has not been studied yet. Methods We conducted a cross-sectional study by using data from the 2005–2010 National Health and Nutrition Examination Survey (NHANES). TCP levels were measured in urine samples from 3385 participants and bone mineral density was obtained by dual X-ray absorptiometry (DXA) lumbar spine and femur scanning. Multiple regression analysis, stratified analysis, curve fitting analysis, and trend tests were used to assess the relationship between TCP and BMD. Result After adjusting for confounding factors, the results of multiple regression analysis only showed that ln-2,4,5-TCP was negatively associated with BMD of lumbar spine. In stratified analyses, Male, Menstruating Female and Menopausal Female were divided into three groups for analysis. The results showed that ln-2,4,5-TCP and ln-2,4,6-TCP were not statistically associated with BMD in total femur, femoral neck, femoral tuberosity, intertrochanteric femur and lumbar spine, which was also confirmed by curve fitting analyses and trend tests. Conclusion This study demonstrated that 2,4,5-TCP and 2,4,6-TCP in urine samples were not significantly associated with BMD in the US population. Therefore, 2,4,5-TCP and 2,4,6-TCP may not be detrimental to BMD.

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The association between hearing threshold and urinary personal care and consumer product metabolites in middle-aged and elderly people from the USA

Cited by 2 publications

References 38 publications

Association of bone mineral density and osteoporosis with trichlorophenol: A national-representative, population-based study

Association of bone mineral density and osteoporosis with trichlorophenol: A national-representative, population-based study

Association of bone mineral density with trichlorophenol: a population-based study

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