The association between hearing impairment and neural envelope encoding at different ages

Goossens, Tine; Vercammen, Charlotte; Wouters, Jan; Wieringen, Astrid Van

doi:10.1016/j.neurobiolaging.2018.10.008

Cited by 41 publications

(58 citation statements)

References 84 publications

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“…Also, PTA Low correlated positively with the FFR ENV_F0 magnitude (i.e., FFR ENV_F0 magnitude increased with low-frequency hearing loss). Therefore, these results are in line with findings that encoding of envelopes at high-gamma frequencies corresponding to the F 0 range declines during aging when peripheral hearing is normal but increases when there is hearing loss (Goossens et al, 2016, 2019).…”

Section: Discussionsupporting

confidence: 91%

“…This suggests that older adults who have age-related hearing loss should show greater declines than those who have normal-hearing. However, evidence shows that hearing loss can reduce neural inhibition that allows greater encoding of F 0 -rate envelope modulations in both animals (Kale and Heinz, 2010; Henry et al, 2014; Zhong et al, 2014) and humans (Anderson et al, 2013; Goossens et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

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Relationship between neural phase-locked responses to speech and perception of speech in noise in young and older adults

Mai

Howell

2019

Preprint

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11Auditory phase-locked responses are affected by aging and it has been proposed that this increases 12 the challenges experienced during speech perception in noise (SPiN). However, the proposal lacks 13 direct support. This issue was addressed by measuring speech-evoked phase-locked responses at 14 subcortical (frequency-following responses, FFRs) and cortical (theta-band phase-locking, θ-PLV) 15 levels, and studying the relationship between the phase-locked responses and SPiN (word report 16 accuracies in spoken sentences in noise) in adults across a wide age-range (19-75 years old). It was 17 found that: (1) FFR magnitudes declined with age after hearing loss was controlled for; (2) θ-PLV 18 increased with age, suggesting cortical hyperexcitability in audition; (3) SPiN correlated positively 19 with FFR magnitudes obtained in quiet and with θ-PLV obtained in noise, suggesting that impacts 20 of age effects (smaller FFR magnitudes and greater θ-PLV) on SPiN perception differ at subcortical 21 and cortical levels. The current study thus provides evidence for different mechanisms at subcortical 22 and cortical levels by which age affects speech-evoked phase-locked activities and SPiN.23

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Relationship between neural phase-locked responses to speech and perception of speech in noise in young and older adults

Mai

Howell

2019

Preprint

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“…Amplified envelope coding following hearing loss has been observed previously both in the auditory periphery (Kale and Heinz, 2010) and at central stages of the auditory system (Zhong et al, 2014;Millman et al, 2017;Heeringa and van Dijk, 2019;Goossens et al, 2019). It is thus possible that effects observed in cortex could be inherited from the periphery.…”

Section: Mechanisms Of Amplified Envelope Coding?mentioning

confidence: 84%

Effects of Sensorineural Hearing Loss on Cortical Synchronization to Competing Speech during Selective Attention

et al. 2020

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When selectively attending to a speech stream in multi-talker scenarios, low-frequency cortical activity is known to synchronize selectively to fluctuations in the attended speech signal. Older listeners with age-related sensorineural hearing loss (presbycusis) often struggle to understand speech in such situations, even when wearing a hearing aid. Yet, it is unclear whether a peripheral hearing loss degrades the attentional modulation of cortical speech tracking. Here, we used psychoacoustics and electroencephalography (EEG) in male and female human listeners to examine potential effects of hearing loss on EEG correlates of speech envelope synchronization in cortex. Behaviorally, older hearing-impaired (HI) listeners showed degraded speech-in-noise recognition and reduced temporal acuity compared with age-matched normal-hearing (NH) controls. During EEG recordings, we used a selective attention task with two spatially separated simultaneous speech streams where NH and HI listeners both showed high speech recognition performance. Low-frequency (Ͻ10 Hz) envelope-entrained EEG responses were enhanced in the HI listeners, both for the attended speech, but also for tone sequences modulated at slow rates (4 Hz) during passive listening. Compared with the attended speech, responses to the ignored stream were found to be reduced in both HI and NH listeners, allowing for the attended target to be classified from single-trial EEG data with similar high accuracy in the two groups. However, despite robust attention-modulated speech entrainment, the HI listeners rated the competing speech task to be more difficult. These results suggest that speech-in-noise problems experienced by older HI listeners are not necessarily associated with degraded attentional selection.

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“…It is noteworthy that older participants in these studies (Anderson et al, 2012;Presacco et al, 2016) had normal peripheral hearing (PTAs ≤ 25 dB HL up to 4 kHz). On the other hand, other evidence has shown that hearing loss may lead to loss of neural inhibition, further leading to greater FFRs in response to envelope modulations at F0 rates compared to normal hearing in both animals (Kale and Heinz, 2010;Henry et al, 2014;Zhong et al, 2014) and humans (Anderson et al, 2013;Goossens et al, 2018). As hearing loss and aging often co-occur (which is the case in the present study, especially in Exp 2), null effect of aging on FFRs here could be ascribed to the combined effects of aging itself and age-related hearing loss.…”

Section: The Role Of Agingmentioning

confidence: 99%

Modulation of phase-locked neural responses to speech during different arousal states is age-dependent

2019

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Phase-locked responses are vital for auditory perception and they may vary with participants' arousal state and age. Two phase-locked neural responses that reflect fine-grained acoustic properties of speech were examined in the current study: the frequency-following response (FFR) to the speech fundamental frequency (F0), which originates primarily from the auditory brainstem, and the theta-band phase-locked response (θ-PLV) to the speech envelope that originates from the auditory cortices. The ways these responses were affected by arousal in adults across a wide age-range (19 ~ 75 years) were examined. Extracts from electroencephalographic (EEG) responses to repeated syllables were classified into either high or low arousal state based on the occurrence of sleep spindles. The magnitudes of both FFRs and θ-PLVs were statistically greater in the high, than in the low, arousal state. The difference in θ-PLV between the two arousal states was significantly associated with sleep spindle density in the young, but not the older, adults. The results show that (1) arousal affects phase-locked processing of speech at cortical/sub-cortical sensory levels; and that (2) there is an interplay between aging and arousal state which indicates that sleep spindles have an age-dependent neuro-regulatory role on cortical processes. The results lay the grounds for studying how cognitive states affect early-stage neural activity in the auditory system across the lifespan.

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The association between hearing impairment and neural envelope encoding at different ages

Cited by 41 publications

References 84 publications

Relationship between neural phase-locked responses to speech and perception of speech in noise in young and older adults

Relationship between neural phase-locked responses to speech and perception of speech in noise in young and older adults

Effects of Sensorineural Hearing Loss on Cortical Synchronization to Competing Speech during Selective Attention

Modulation of phase-locked neural responses to speech during different arousal states is age-dependent

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