The association between diabetes mellitus and urinary incontinence in adult women

Izci, Yenal; Topsever, Pınar; Fílíz, Tuncay Müge; Çınar, Nursan; Uludağ, Cefariye; Lagro‐Janssen, Toine

doi:10.1007/s00192-009-0888-8

Cited by 57 publications

(66 citation statements)

References 23 publications

(54 reference statements)

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“…1–4 While urinary incontinence has been shown to be more common in women with diabetes, 5,6 there is a dearth of literature regarding the influence of glycemic control on urinary incontinence.…”

Section: Introductionmentioning

confidence: 99%

Diabetes, Glycemic Control, and Urinary Incontinence in Women

Wang¹,

Lefevre²,

Hacker³

et al. 2015

Female Pelvic Medicine &Amp; Reconstructive Surgery

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OBJECTIVES To estimate the association between urinary incontinence and glycemic control in women ages 20 to 85. METHODS We included 7,270 women from the 2005–2010 National Health and Nutrition Examination Survey, stratified into three groups of glycemic control defined by hemoglobin A1c (HbA1c): i) those below the diagnostic threshold (HbA1c<6.5%), ii) those with relatively controlled diabetes (HbA1c 6.5–8.5%), and iii) those with poorly controlled diabetes (HbA1c>8.5%) to allow for a different relationship between glycemic control and urinary incontinence within each group. The primary outcomes were the presence of any, only stress, only urgency, and mixed urinary incontinence. We calculated adjusted risk ratios using Poisson regressions with robust variance estimates. RESULTS The survey-weighted prevalence was 52.9% for any, 27.2% for only stress, 9.9% for only urgency, and 15.8% for mixed urinary incontinence. Among women with relatively controlled diabetes, each one-unit increase in HbA1c was associated with a 13% (95% CI: 1.03–1.25) increase for any urinary incontinence and a 34% (95% CI 1.06–1.69) increase in risk for only stress incontinence but was not significantly associated with only urgency and mixed incontinence. Other risk factors included body mass index, hormone replacement therapy, smoking, and physical activity. CONCLUSIONS Worsening glycemic control is associated with an increased risk for stress incontinence for women with relatively controlled diabetes. For those either below the diagnostic threshold or with poorly controlled diabetes, the risk may be driven by other factors. Further prospective investigation of HbA1c as a modifiable risk factor may motivate measures to improve continence in women with diabetes.

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Section: Introductionmentioning

confidence: 99%

Diabetes, Glycemic Control, and Urinary Incontinence in Women

Wang¹,

Lefevre²,

Hacker³

et al. 2015

Female Pelvic Medicine &Amp; Reconstructive Surgery

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“…The positive relevance between cystocele and SUI was found to be statistically significant and the result is in accordance with the literature. (p<0.05) [13][14][15] . The loss in the support of urethra and cervix vesicae can be affiliated with the loss (for example a paravaginal defect) or the loosening of (for example the change in type, amount or quality of collagen in levator fascia) endopelvic fascia, as well as the denervation with tonus loss in the levitor ani muscles (for example instances associated with delivery trauma on the vagina) 16,17 .…”

Section: Discussionmentioning

confidence: 99%

“…In 15.21% of the cases DM was existent and the incontinence types in these cases were monitored in similar rates. DM is an independent risk factor for UI and increases the UI risk 2.5-fold 14 .…”

Section: Discussionmentioning

confidence: 99%

Urinary incontinence and risk factors

Yaz¹,

Kurt²,

Demirtaş³

et al. 2015

Cumhuriyet Med J

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SUMMARYObjective: Examining the effects of body mass index (BMI), parity, method of delivery, defects in pelvic floor, diabetes mellitus on the types of incontinence in Urinary incontinence (UI) cases. Method: 230 UI cases were evaluated in this study. Questions asked to the cases to determine the age, parity and the type of incontinence. Incontinence was diagnosed with history. Additionally, gynecological examination findings, fasting and postprandial blood glucose (FBG-PPG) and hemoglobin A1c(HbA1c) levels were recorded. Results: The average age was 49.63 ± 10.68; gravida 4.21 ± 2.68; parity 3.59 ± 2.51. The average BMI was determined as 29.86 ± 4.25. In 94 (40.86%) of the patients had stress incontinence(SUI), 70 (30.43%) urge incontinence(UUI) and 66 (28.69%) mixed incontinence. Pelvic floor defects was detected at 94(40.86%) of the cases. Whereas SUI was observed more prominently in juvenile cases with low parity accompanied by anatomic pelvic deformity; the divergence disappears with the introduction of no pelvic floor defect and with 5 or more instances of gestation and delivery. In 114 (49.56%) cases obesity + morbid obesity was existent. In this group, the types of incontinence were similar; in 116 (51.44%) of the cases with normal weight, SUI was more prevalent. It was observed that there was impaired fasting glucose(IFG) in 68 (29.56%) of cases impaired glucose tolerance(IGT) in 49 (21.30%) of cases and diabetes mellitus in 35 (15.21%) of cases. In IGT cases, SUI was more prevalent. UUI was observed more frequently than MUI and SUI in diabetes cases; however the divergence didn't bear any statistical significance (p>0.05). Conclusion: SUI is prevalent in juvenile cases with IFG and IGT, low parity and delivery, anatomic defects due to traumatic birth. The divergence disappears with advanced age, high parity and delivery. MUI is observed with advanced age more frequently. UUI is observed more frequently in advanced age patient with DM.Keywords: Impaired glucose tolerance, urinary incontinence, risk factors ÖZET Amaç: Üriner inkontinanslı hastalarda vücut kitle indeksi, parite, doğum şekli, pelvik taban defektleri ve gizli veya aşikar diabetin inkontinans tiplerinin dağılımı üzerindeki etkisinin araştırılması. Yöntem: Toplam 230 üriner inkontinans olgusu değerlendirildi. Olgulara; yaş, gebelik, parite, Diabetes Mellitus(DM), gestasyonel diabet ve inkontinans tipini saptamaya yönelik soru formları dolduruldu. Ayrıca boy, kilo, jinekolojik muayene bulguları, açlık-tokluk kan şekeri (AKŞ-TKŞ) ve hemoglobin A1c(HbA1c) ölçümleri değerlendirildi. Bulgular: Olgularda ortalama yaş 49,63 ± 10,68; gravida 4,21 ± 2,68; parite 3,59 ± 2,51; vücut kitle indeksi (VKİ) ortalaması 29,86 ± 4,25 saptanmıştır. Olguların %40,9'unda (94) stres, %30,4'ünde (70) urge, %28,7'sinde (66) mikst inkontinans saptanmıştır. Pelvik taban bozukluğu 94 (%40,86) olguda tespit edildi. Pelvik anatomik bozuklukların eşlik ettiği, genç yaş, düşük parite ve doğumda stres üriner inkontinans (SUİ) baskınlığı ön plandayken; pelvik taban defekti o...

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“…When population-based studies have included the consideration of blood glucose levels, it appears that one in three people is living with unrecognized or undiagnosed diabetes [4,10,11]. Undetected diabetes in seniors can have serious implications for management because of the higher risk of falls, urinary incontinence, and hospitalizations associated with this disease [1,[11][12][13][14][15]. Furthermore, the economic burden associated with a case of undetected diabetes is estimated to be 8 times that of a person with prediabetes [16].…”

Section: Introductionmentioning

confidence: 99%