The association between childhood irritability and liability to substance use in early adolescence: a 2-year follow-up study of boys at risk for substance abuse

Tarter, Ralph E.; Blackson, Timothy C.; Brigham, Janet; Moss, Howard B.; Caprara, Gian Vittorio

doi:10.1016/0376-8716(95)01175-6

Cited by 78 publications

(40 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the current study is unique in that we extended those effects to show that it is stressors' effects on externalizing symptoms (not internalizing symptoms) that seems to connect it to the development of substance-use disorders. Although our analyses do not conclusively rule out specifi c aspects of internalizing symptoms, such as depression or anger (McCreary and Sadava, 1999;Tarter et al, 1995), they do rule in a novel pathway from stressful life events to substance use.…”

Section: Discussioncontrasting

confidence: 64%

“…Broadly, each theory hypothesizes that exposure to stressors produces elevations in negative emotions (or internalizing symptoms), and these increases in negative emotions in turn lead to increased substance use and risk for substance-use disorders. However, the few prospective studies of the effects of adolescent internalizing symptoms on substance-use disorders have shown no effects (e.g., Chassin et al, 1999) or have suggested that only certain aspects, such as anger, are the specifi c mechanism of effect (McCreary and Sadava, 1999;Tarter et al, 1995). For example, anger has been theorized to lead to substance use either through poor adaptive coping skills (Wills et al, 1999) or through affi liation with deviant peers (Swaim et al, 1989).…”

Section: Theoretical Mediatorsmentioning

confidence: 99%

See 1 more Smart Citation

Adolescent Stressors, Psychopathology, and Young Adult Substance Dependence: A Prospective Study

King

Chassin

2008

J. Stud. Alcohol Drugs

View full text Add to dashboard Cite

ABSTRACT. Objective: There is much theory, but sparse empirical evidence, supporting the notion that internalizing symptoms and negative affect are the mechanism by which exposure to stressful life events infl uence the development of substance-use disorders in adolescence and young adulthood. However, many empirical studies have shown that, in addition to elevations in internalizing symptoms, exposure to stressful life events also produces elevations in externalizing behaviors and conduct problems, which are important risk factors for substance-use disorders. The current study tested adolescent externalizing and internalizing symptoms as competitive mediators of the effects of stressors on young adult drug dependence. Method: Data from an ongoing study of children of alcoholics (n = 223) and matched controls (n = 204) were collected in two annual interviews in adolescence and two follow-ups in young adulthood. Results: Experiencing stressful life events during adolescence led to increases in both externalizing and internalizing symptoms, but only externalizing symptoms mediated the later effects of adolescent stressors on young adult drug dependence. Conclusions: These fi ndings suggest that understanding how stressors produce elevations in behavioral problems may provide important insights into understanding how broad environmental risk factors lead to substance dependence and suggests that processes other than affect regulation may operate in the pathway from the experiences of stressors to substance use and disorder. (J. Stud. Alcohol Drugs 69: [629][630][631][632][633][634][635][636][637][638] 2008) T

show abstract

Section: Discussioncontrasting

confidence: 64%

Section: Theoretical Mediatorsmentioning

confidence: 99%

Adolescent Stressors, Psychopathology, and Young Adult Substance Dependence: A Prospective Study

King

Chassin

2008

J. Stud. Alcohol Drugs

View full text Add to dashboard Cite

show abstract

“…This fact, suggests that in the last decades N1 and N2 components have been studied as possible endophenotypes or bio-markers for different disorders and in some cases for recovery index: namely, in schizophrenia (Hegerl et al 1988;Haig et al 1997;Potts et al 1998a;Shelley et al 1999;Ford et al 2001;Brown et al 2002;Gilmore et al 2005;Neuhaus et al 2013), dementia (Verma et al 1989), Alzheimer (Sumi et al 2000), epilepsy and AED effects (Akaho 1996;Ford et al 2001;Lucchesi et al 2003), alcohol (Brigham et al 1997;Cohen et al 2002) and substance abuse (Tarter et al 1995;Brigham et al 1997), psychosis (Valkonen-Korhonen et al 2003), panic disorder (Wise et al 2009), Parkinson's disease (Wright et al (1996), ADHD (Johnstone et al 2001;Tsai et al 2012), stroke (Hirata et al 1996) and vascular cognitive impairment (van Harten et al 2006), myotonic dystrophy (Kazis et al 1996;Tanaka et al 2012), head injury (Reinvang et al 2000;Segalowitz et al 2001), (Guney et al 2009), amyotrophic lateral sclerosis (Ogawa et al 2009) and multiple sclerosis (Whelan et al 2010), more recently fragile X syndrome treatment (Schneider et al 2013), and bipolar disorder (Hamm et al 2013). …”

Section: Discussionmentioning

confidence: 99%

The development of the N1 and N2 components in auditory oddball paradigms: a systematic review with narrative analysis and suggested normative values

et al. 2014

View full text Add to dashboard Cite

Auditory event-related potentials (AERPs) are widely used in diverse fields of today's neuroscience, concerning auditory processing, speech perception, language acquisition, neurodevelopment, attention and cognition in normal aging, gender, developmental, neurologic and psychiatric disorders. However, its transposition to clinical practice has remained minimal. Mainly due to scarce literature on normative data across age, wide spectrum of results, variety of auditory stimuli used and to different neuropsychological meanings of AERPs components between authors. One of the most prominent AERP components studied in last decades was N1, which reflects auditory detection and discrimination. Subsequently, N2 indicates attention allocation and phonological analysis. The simultaneous analysis of N1 and N2 elicited by feasible novelty experimental paradigms, such as auditory oddball, seems an objective method to assess central auditory processing. The aim of this systematic review was to bring forward normative values for auditory oddball N1 and N2 components across age. EBSCO, PubMed, Web of Knowledge and Google Scholar were systematically searched for studies that elicited N1 and/or N2 by auditory oddball paradigm. A total of 2,764 papers were initially identified in the database, of which 19 resulted from hand search and additional references, between 1988 and 2013, last 25 years. A final total of 68 studies met the eligibility criteria with a total of 2,406 participants from control groups for N1 (age range 6.6-85 years; mean 34.42) and 1,507 for N2 (age range 9-85 years; mean 36.13). Polynomial regression analysis revealed that N1 latency decreases with aging at Fz and Cz, N1 amplitude at Cz decreases from childhood to adolescence and stabilizes after 30-40 years and at Fz the decrement finishes by 60 years and highly increases after this age. Regarding N2, latency did not covary with age but amplitude showed a significant decrement for both Cz and Fz. Results suggested reliable normative values for Cz and Fz electrode locations; however, changes in brain development and components topography over age should be considered in clinical practice.

show abstract

“…In the BSFT group, the difference in change in salivary cortisol level had a significant negative correlation with the difference in change on most of the STAXI subscales, which could support the view that an inverse relation exists between cortisol secretion after awakening and aggressive behaviour (see also [12][13][14][15]. Thus the difference in change in morning salivary cortisol level correlated significantly and positively with the differences in change on all the SF-36 subscales measuring psychological health, which would generally support the view that there is a close relation between cortisol secretion and mental health in adolescents (11)(12)(13)(14)(15).…”

Section: Discussionmentioning

confidence: 52%

“…Moss and others found a diminished salivary cortisol response in children that correlated to the magnitude of behavioural problems (11). Other studies in children have also found reduced basal cortisol concentrations associated with anger, irritability, hostility, and CD severity (12)(13)(14)(15); some studies, however, reported the absence of these findings (16). Thus environmental factors are nearly as important as heritable factors in accounting for the variations in plasma cortisol concentrations (11,17).…”

mentioning

confidence: 99%

Influence of Family Therapy on Bullying Behaviour, Cortisol Secretion, Anger, and Quality of Life in Bullying Male Adolescents: A Randomized, Prospective, Controlled Study

et al. 2006

View full text Add to dashboard Cite

Objective:To determine the influence of brief strategic family therapy (BSFT) on salivary cortisol, anger, and health-related quality of life (QoL) in adolescent boys with bullying behaviour. Method:We selected a sample of 72 boys demonstrating bullying behaviour from the general population and treated 36 with BSFT for 12 weeks. The other 36 boys formed the control group. Primary outcome measures were salivary cortisol concentration 15 to 30 minutes after awakening and changes on the subscales of the State-Trait Anger Expression Inventory (STAXI) and the Health Survey (SF-36). Results:After 12 weeks' treatment, we observed a significant reduction in bullying behaviour in the BSFT group (P = 0.017) and in the mean values (according to the intent-to-treat principle) for salivary cortisol concentration (P < 0.001). The BSFT group also showed significantly greater change on the STAXI subscales State-Anger (P < 0.001), Trait-Anger (P < 0.001), Anger-Out (P < 0.001), and Anger-Control (P < 0.001). Treatment with BSFT also resulted in significant improvement on the SF-36 subscales for Vitality (P < 0.001), Social Functioning (P < 0.001), Role-Emotional (P < 0.001), and Mental Health (P < 0.001).Conclusions: BSFT effectively influenced bullying behaviour, salivary cortisol concentration, anger, and health-related QoL in adolescent bullying boys. (Can J Psychiatry 2006;51:355-362) Information on funding and support and author affiliations appears at the end of the article. Clinical Implication· BSFT effectively reduces bullying behaviour, salivary cortisol level, and anger and improves health-related quality of life in bullying male adolescents. Limitations· The sample size was relatively small. · The sample consisted only of male adolescents. · Observance of the guidelines for sampling saliva was not checked.

show abstract

The association between childhood irritability and liability to substance use in early adolescence: a 2-year follow-up study of boys at risk for substance abuse

Cited by 78 publications

References 37 publications

Adolescent Stressors, Psychopathology, and Young Adult Substance Dependence: A Prospective Study

Adolescent Stressors, Psychopathology, and Young Adult Substance Dependence: A Prospective Study

The development of the N1 and N2 components in auditory oddball paradigms: a systematic review with narrative analysis and suggested normative values

Influence of Family Therapy on Bullying Behaviour, Cortisol Secretion, Anger, and Quality of Life in Bullying Male Adolescents: A Randomized, Prospective, Controlled Study

Contact Info

Product

Resources

About