The Association Between Blood Coagulation Markers, Atherothrombosis and Dementia

Gupta, Akhil; Pansari, K

doi:10.1111/j.1742-1241.2003.tb10437.x

Cited by 9 publications

References 71 publications

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Current awareness in geriatric psychiatry

2003

Int J Geriat Psychiatry

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of geriatric psychiatry. Each bibliography is divided into 9 sections: 1 Books, Reviews & Symposia; 2 General; 3 Assessment; 4 Epidemiology; 5 Therapy; 6 Care; 7 Dementia; 8 Depression; 9 Psychology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted

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Current awareness in geriatric psychiatry

2003

Int J Geriat Psychiatry

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The Epidemiology and Genetics of Vascular Dementia

Naj

2016

Translational Cardiometabolic Genomic Medicine

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Association between multimorbidity status and incident dementia: a prospective cohort study of 245,483 participants

Zhang

Aerqin

et al. 2022

Transl Psychiatry

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Multimorbidity (the presence of two or more long-term conditions [LTCs]) was suggested to exacerbate the neuronal injuries. The impact of multimorbidity on dementia has not been fully elucidated. We aimed to investigate the association between multimorbidity and dementia risk. We used the prospective data from 245,483 UK Biobank participants during a 9-year follow-up. Multimorbidity status was evaluated based on the LTC counts and multimorbidity patterns. Cox regression models adjusted for potential confounders were used to examine the associations of multimorbidity status with all-cause dementia (ACD), Alzheimer’s disease (AD) and vascular dementia (VD). Participants with multimorbidity at baseline had higher risks of ACD and VD, and the risks were elevated with the increase of LTC counts (ACD: hazard ratios [HR] = 1.15, 95% confidence intervals [CI] = 1.01–1.31 with 2 LTCs; HR = 1.18, CI = 1.01–1.39 with 3 LTCs; HR = 1.65, CI = 1.44–1.88 with ≥4 LTCs; VD: HR = 1. 66, CI = 1.24–2.21 with 2 LTCs; HR = 2.10, CI = 1.53–2.88 with 3 LTCs; HR = 3.17, CI = 2.43–4.13 with ≥4 LTCs). Participants with ≥4 LTCs also had a higher risk of AD (HR = 1.34, CI = 1.08–1.66]. Participants with the cardio-cerebrovascular/respiratory/metabolic/musculoskeletal/depressive multimorbidity were 1.46, 1.28, and 2.50 times more likely to develop ACD (HR = 1.46, 95% CI = 1.28–1.67), AD (HR = 1.28, CI = 1.04–1.58), and VD (HR = 2.50, CI = 1.90–3.27), respectively. Those with tumor/genitourinary/digestive disorders had a 11% higher hazard of ACD (HR = 1.11, CI = 1.00–1.24) and a 73% elevated risk of VD (HR = 1.73, CI = 1.37–2.18). The prevention of LTC accumulation and the identification of specific multimorbidity patterns might be beneficial to the prevention of dementia and its subtypes, AD as well as VD.

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The Association Between Blood Coagulation Markers, Atherothrombosis and Dementia

Cited by 9 publications

References 71 publications

Current awareness in geriatric psychiatry

Current awareness in geriatric psychiatry

The Epidemiology and Genetics of Vascular Dementia

Association between multimorbidity status and incident dementia: a prospective cohort study of 245,483 participants

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