The Association between Atopic Dermatitis and Depressive Symptoms in Korean Adults: The Fifth Korea National Health and Nutrition Examination Survey, 2007-2012

Kim, Sewon; Lee, Jee Yon; Oh, Jung Hyub; Chekal, Lan; Lee, Duk Chul

doi:10.4082/kjfm.2015.36.6.261

Cited by 23 publications

(37 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This nationwide population-based study of Korean adults found that 1.8% of participants had AD, which is quite similar to the results of a recent study showing a 1.88% of AD prevalence in Korean adults [21]. This finding is consistent with previous reports that AD is one of the most common skin diseases, with a prevalence of 1% to 3% in adults [22,23].…”

Section: Discussionsupporting

confidence: 91%

Association of Perceived Stress with Atopic Dermatitis in Adults: A Population-Based Study in Korea

Park

Kim

2016

IJERPH

View full text Add to dashboard Cite

Atopic dermatitis (AD) is a widely prevalent skin disease that affects both children and adults. The aim of the study was to assess the association of perceived stress (single-item, self-reported) with AD (self-reported) in a sample of Korean adults using a cross-sectional research design. A cross-sectional study was conducted using data from 33,018 adults aged 20 years and older collected in the 2007–2012 Korea National Health and Nutrition Examination Surveys (KNHANES). An increased level of self-reported stress was positively associated with an increased prevalence of AD in Korean adults (p for trend <0.001). After adjusting for covariates, the odds ratios (ORs) of AD among participants reporting high and very high levels of stress were 1.81 (95% confidence interval (CI): 1.22, 2.67) and 2.17 (95% CI: 1.38, 3.42), respectively, compared with those who reported low levels of stress. This study found a statistically significant association between perceived stress and AD among Korean adults.

show abstract

Section: Discussionsupporting

confidence: 91%

Association of Perceived Stress with Atopic Dermatitis in Adults: A Population-Based Study in Korea

Park

Kim

2016

IJERPH

View full text Add to dashboard Cite

show abstract

“…One might speculate that itch, skin pain and sleep disturbances in combination with typical AE skin lesions, cause psychologic distress which may result in development of depression, anxiety and/or impaired QoL . There is still debate whether the depressive and anxious symptoms result from physical discomfort and psychosocial burden of the skin disease or whether these disorders are based on shared inflammatory pathomechanisms …”

Section: Discussionmentioning

confidence: 99%

“…50,51 There is still debate whether the depressive and anxious symptoms result from physical discomfort and psychosocial burden of the skin disease or whether these disorders are based on shared inflammatory pathomechanisms. 10,52,53 Further investigations are needed to investigate therapeutical effects of new or upcoming treatment options for AE on mental health in AE patients. 54 Trial results from phase 3 dupilumab, a monoclonal antibody against interleukin 4, showed that the proportion of patients with moderate-to-severe AE who reported depression and anxiety was significantly reduced in the active arm compared to the placebo arm.…”

Section: Discussionmentioning

confidence: 99%

Depression, anxiety and quality of life in subjects with atopic eczema in a population‐based cross‐sectional study in Germany

Treudler¹,

Zeynalova

Riedel-Heller

et al. 2020

Acad Dermatol Venereol

View full text Add to dashboard Cite

Background Atopic eczema (AE) may be associated with several mental health problems. In Germany, existing data from selected patient cohorts may lead to misestimation of the problem. Objectives We aimed to cross‐sectionally determine associations of AE with depression, anxiety, quality of life (QoL) and social interactions in subjects from the population‐based LIFE‐Adult‐Study. Methods Subjects underwent standardized interviews (medical history) and answered standardized questionnaires [Centre of Epidemiologic studies‐Depression scale (CES‐D), Generalized Anxiety Disorder (GAD‐7), Lubben Social Network Scale (LSNS), Short Form Health Survey (SF‐8)]. We compared data from subjects with AE with those from subjects with selected other chronic/disabling diseases (cardiovascular, diabetes, cancer) and adjusted for selected sociodemographic parameters. Multivariate binary logistic regression was used for categorical variables, linear regression for continuous variables. Results Out of 9104 adults included (57% female, median age 54 years), 372 (4.1%) had a history of AE. Compared with controls, subjects with AE showed higher scores for depressive symptoms (9.3% vs. 6.3%; P < 0.001) and anxiety (8.4% vs. 5.6%, P < 0.001). Odds ratio (OR) was 1.5 [CI 1.0; 2.3] (P = 0.031) for depression, which was comparable to OR in patients with a history of cancer (OR 1.6 [1–2.3], P = 0.001. OR for anxiety in AE was 1.5 [1.0; 2.2], P < 0.049, which was slightly higher than in diabetes mellitus (OR 1.2) and stroke (OR 1.4). Other than in diabetes and/or stroke, we did not find a significant association between AE and social isolation. QoL scores were lower in AE than in controls (mean 46.9 vs. 48.0, P < 0.001 for physical and 50.6 vs. 52.5, P < 0.001 for mental components). Conclusions Subjects with AE showed higher values for depression and anxiety as well as lower QoL scores compared to controls. With regard to depression, odds in AE and cancer were hardly different. Medical care of AE patients should therefore include mental health evaluation and treatment if indicated.

show abstract

“…It is known that mental disorders are more common in female dermatological patients in general (18). A South Korean study reported a surprisingly high prevalence of depression (10.4%), anxiety (9.8%) and somatization (11.7%) in young adult males with AD (19) but it was conducted only among male conscripts and had a small study sample (n = 1 517). Furthermore, the psychiatric diagnoses were defined and classified by military health officers, which may have led to overestimation of the prevalence of these disorders.…”

Section: Discussionmentioning

confidence: 99%

Adult Patients with Atopic Eczema have a High Burden of Psychiatric Disease: A Finnish Nationwide Registry Study

Kauppi¹,

Jokelainen²,

Timonen³

et al. 2019

Acta Derm Venerol

View full text Add to dashboard Cite

Atopic dermatitis is associated with several comorbidities. In this study we investigated psychiatric comorbidities of adult patients with atopic dermatitis. Our study shows that at least one psychiatric diagnosis was found in 17.2% of the atopic dermatitis patients. Actually, every mental diagnosis studied was more common in patients with atopic dermatitis compared to the melanocytic naevi controls. We report, for the first time, that atopic dermatitis is associated with both schizophrenia and bipolar disorders. Since psychiatric morbidity is significant in patients with atopic dermatitis, assessing patients' mental health status should be considered as part of standard care. Atopic dermatitis is associated with several comorbidities. Epidemiological studies on psychiatric comorbidities in adult atopic dermatitis patients are sparse. We analyzed psychiatric comorbidities in a Finnish nationwide adult atopic dermatitis cohort. The study included 57,690 adult patients with atopic dermatitis as cases and 40,363 individuals diagnosed with melanocytic naevi as controls. Data was obtained from the statutory Finnish Care Register for Health Care. The prevalence of preselected comorbidities between the atopic dermatitis and control groups was compared. Every psychiatric disorder studied was more common in patients with atopic dermatitis than in controls. At least one psychiatric diagnosis was found in 17.2% of the atopic dermatitis patients and 13.1% of controls. Psychiatric morbidity is significant in patients with atopic dermatitis and therefore assessing patients' mental health status should be considered as part of standard care.

show abstract

The Association between Atopic Dermatitis and Depressive Symptoms in Korean Adults: The Fifth Korea National Health and Nutrition Examination Survey, 2007-2012

Cited by 23 publications

References 13 publications

Association of Perceived Stress with Atopic Dermatitis in Adults: A Population-Based Study in Korea

Association of Perceived Stress with Atopic Dermatitis in Adults: A Population-Based Study in Korea

Depression, anxiety and quality of life in subjects with atopic eczema in a population‐based cross‐sectional study in Germany

Adult Patients with Atopic Eczema have a High Burden of Psychiatric Disease: A Finnish Nationwide Registry Study

Contact Info

Product

Resources

About