The association between artificial light at night and gestational diabetes mellitus: A prospective cohort study from China

Liao, Junhao; Yu, Chuan; Cai, Jiarui; Tian, Run; Li, Xingyue; Wang, Hong; Li, Lin; Song, Guishuang; Fu, Leyao; Li, Xinxi; Ge, Qiaoyue; Zhang, Ling; Liu, Zhenmi; Xiao, Chenghan

doi:10.1016/j.scitotenv.2024.170849

Cited by 1 publication

(1 citation statement)

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“…In the United States, the risk associated with GDM has been correlated with pre-sleep exposure to light, as measured by wrist-worn activity monitors ( 37 ). Consistent with our findings, a prospective cohort study in Sichuan Province, China, utilizing satellite data to estimate outdoor ALAN exposure, offered a broader perspective on environmental exposure ( 38 ). Furthermore, a study conducted in Hefei City revealed that outdoor ALAN was associated with elevated early-pregnancy glucose homeostasis markers, yet it did not correlate with GDM risk ( 39 ).…”

Section: Discussionsupporting

confidence: 88%

Outdoor artificial light at night exposure and gestational diabetes mellitus: a case–control study

Sun,

Ye,

Liu

et al. 2024

Front. Public Health

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ObjectiveThis study aims to explore the association between outdoor artificial light at night (ALAN) exposure and gestational diabetes mellitus (GDM).MethodsThis study is a retrospective case–control study. According with quantiles, ALAN has been classified into three categories (Q1-Q3). GDM was diagnosed through oral glucose tolerance tests. Conditional logistic regression models were used to evaluate the association between ALAN exposure and GDM risk. The odds ratio (OR) with 95% confidence interval (CI) was used to assess the association. Restricted cubic spline analysis (RCS) was utilized to investigate the no liner association between ALAN and GDM.ResultsA total of 5,720 participants were included, comprising 1,430 individuals with GDM and 4,290 matched controls. Pregnant women exposed to higher levels of ALAN during the first trimester exhibited an elevated risk of GDM compared to those with lower exposure levels (Q2 OR = 1.39, 95% CI 1.20–1.63, p < 0.001); (Q3 OR = 1.70, 95% CI 1.44–2.00, p < 0.001). Similarly, elevated ALAN exposure during the second trimester also conferred an increased risk of GDM (second trimester: Q2 OR = 1.70, 95% CI 1.45–1.98, p < 0.001; Q3 OR = 2.08, 95% CI 1.77–2.44, p < 0.001). RCS showed a nonlinear association between ALAN exposure and GDM risk in second trimester pregnancy, with a threshold value of 4.235.ConclusionOutdoor ALAN exposure during pregnancy is associated with an increased risk of GDM.

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Section: Discussionsupporting

confidence: 88%