The Association between Arterial Stiffness, Initial Stroke Severity, and 3-Week Outcomes in Patients with Ischemic Stroke

Abstract

Objectives: Vascular compliance is emerging as a useful cardiovascular risk factor.The aim of this study was to investigate the association between arterial stiffness and stroke severity at presentation and at three weeks. Methods:From an initial sample of 73 patients, 42 were included (55% male, mean age 71 years) with acute ischaemic stroke, over a 15 month period. Stroke subtypes were classified into LACI, PACI and POCI. Arterial stiffness was measured by QKD using 24-hour ambulatory blood pressure and ECG monitoring. The measured QKD values were then corrected for a heart rate of 60bpm and a systolic blood pressure (SBP) of 100 mmHg (QKD 100-60 ). Stroke severity was assessed on admission and after 3 weeks, using the National Institute of Health Stroke Scale (NIHSS). Results:There was a non-significant weak correlation between initial stroke severity and QKD 100-60 (r= -0.3, p = 0.08). This correlation was weaker at 3 weeks (r= 0.125, p=0.47). There was no difference in NIHSS at week 0 and 3, or QKD 100-60, between the different stroke types (LACI, PACI and POCI) or dipper versus non-dippers and reverse dippers. Conclusions:This study highlights the need for further research into the association between QKD and initial stroke severity.

Correlation of Obesity and Overweight with Cervical Vascular Function Among Healthy Populations

“…17 According to studies, vascular compliance is higher in healthy individuals and lower in patients with ischemic cerebrovascular and advanced disease. 18 Therefore, pulsatility index and blood flow velocity measurements can, to some extent, indicate vascular function. The findings of this study demonstrate that weight gain and obesity have no impact on the pulsatility index for ICA, VA, and BA.…”

A Study on the Association between Korotkoff Sound Signaling and Chronic Heart Failure (CHF) Based on Computer-Assisted Diagnoses

“…The authors found a strong association between QKD h and cardiovascular disease, which is suggested to be used as a diagnostic basis for stroke. Ormerod et al [ 11 ] found that QKD parameters were strongly associated with stroke caused by aortic sclerosis, while the relationships between cardiac embolism and small artery occlusion subtypes were not clear. Ramakrishnan [ 12 ] studied the effects of age and gender on the amplitude of KS, suggesting that the amplitude of KS could be used to predict atherosclerosis.…”