The assessment of the accuracy of clinical preoperative lymph node

Abstract

Purpose:The aim of the present study is to assess the accuracy of clinical preoperative lymph node and to define the degree of relation between the clinical preoperative assessment and histopathological examination in patients with head and neck cancer and cN+.Methods:This retrospective study was performed on 125 patients (85 males and 40 females) at the Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Zhengzhou University, between December 2012 and December 2014.Result:Of all the patients who underwent neck dissection, 37 were found with no neck metastasis. Positive or suspected lymph nodes were detected at computed tomography (CT) in 44 and detected at ultrasonogram diagnosis (USG) in 38 of 125 patients, and the necks were assessed as normal in 55 (44%) by both USG and CT.Conclusion:Further investigation is needed to evaluate the rates of overall survival and disease-free survival of these N0 patients with neck dissection.

Pre-operative cellular dissociation grading in biopsies is highly predictive of post-operative tumour stage and patient outcome in head and neck squamous cell carcinoma

“…This might be due to the high discordance rate of pre-operative clinical cT and cN stage compared with post-operative pT and pN in 36%, respectively, 32% cases—a finding which confirms previous studies in HNSCC studies showing comparably low concordance rates between clinical and pathological staging. 6 , 48 , 49 Furthermore, in our study, the subgroup of clinically early HNSCC in UICC stages I and II 20% of cN0 necks revealed occult nodal metastasis only detected by pathological examination. Considering the ongoing discussion if clinically nodal-negative necks should be treated by elective neck dissection or by watchful waiting strategies, these results support the notion and confirm previous studies that clinical staging in its current form is not a valuable predictive tool for treatment planning in these patients, 10 , 11 , 50 , 51 as it lacks the necessary sensitivity for detection of metastatic disease.…”

An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma

“…Given that the majority of OSCC patients in our data set exhibited habits such as smoking, alcohol consumption, and betel nut chewing, which are known confounders of the oral microbiome, we have excluded their effects in the microbiome analysis. OSCC patients were precisely diagnosed by magnetic resonance imaging and histopathology was used for cancer staging . The stages of OSCC were classified according to the seventh edition of the American Joint Committee on Cancer staging manual .…”