The assessment of relationship between mitral valve prolapse and panic disorder

Tamam, Lut; Özpoyraz, Nurgül; Şan, Mustafa; Bozkurt, Atila

doi:10.1016/s0924-977x(99)80397-6

Cited by 5 publications

(9 citation statements)

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“…16 Anxiety disorders, especially PD shows a co-morbidity with MVP. 1,15 MVP has been observed more frequently than expected among patients with panic attacks. 17 Although there is a controversy regarding the comorbidity of MVP with PD, our study has confirmed that there is a tendency towards the co-morbidity of MVP-PD with a relative increase of our study group of 45% comparing to that of control group and the contribution of anterior mitral leaflet prolapse to PD.…”

Section: Discussionmentioning

confidence: 72%

“…These patients were evaluated for panic disorder, which was defined according to the criteria of the American Psychiatric Association as at least three panic attacks within a 3-week period or one panic attack followed by fear of subsequent panic attacks for at least one month. 1,15 In statistical analysis, values of selected variables were summarized by standard descriptive statistics and expressed as mean  SD. Independent-Samples T test (Mann-Whitney U test when Levene test is significant) and chi-square test were used to compare continuous and categorical variables between groups, respectively.…”

Section: Methodsmentioning

confidence: 99%

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Anterior Mitral Valve Prolapse Contributes to Mitral Regurgitation and Panic Disorder

Ulusoy¹

2012

JIUMF

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Objective: Mitral valve prolapse is affecting 2,4% of general population which shows similar prevalence, age and gender distribution and share common nonspecific symptoms with panic disorder. The aim of this prospective study is to investigate the contribution of the anterior mitral leaflet prolapse to mitral regurgitation and panic disorder. Material and Methods: Ninety-six patients, who were finally diagnosed as having noncardiac chest pain with anterior mitral valve prolapse during the evaluation of chest pain, palpitation and fatigue were assessed for panic disorder. Results: From 96 patients with mitral valve prolapse (mean age 40±8 years), 46 (48%) had panic disorder and 32 (33%) had mitral regurgitation. Majority of the patients were female (53%). 48 % of the patients with panic disorder had mitral regurgitation. Among 32 patients with mitral regurgitation, 22 (69%) had panic disorder. The incidence of panic disorder in patients with mitral regurgitation was 69%. Among those with panic disorder, 48% had mitral regurgitation. There was a significant correlation between mitral regurgitation and panic disorder (p=0.004).Conclusion: This study has demonstrated the possible contribution of the anterior mitral leaflet prolapse to mitral regurgitation and panic disorder. Panic disorder and mitral valve prolapse presents a co-morbidity, which deserves further clinical investigations. Key Words: Mitral Valve Prolapse; Panic Disorder; Mitral Regurgitation. Anteriyor Mitral Kapak Prolapsusu Mitral Yetersizlik ve Panik Bozukluğa Katkıda BulunmaktadırAmaç: Mitral kapak prolapsusu genel populasyonun %2.4'ünü etkilemektedir. Panik bozuklukla benzer sıklık, yaş ve cinsiyet dağılımı göstermekte ve ortak nonspesifik semptomları paylaşmaktadır. Bu prospektif çalışmada anteriyor mitral kapak prolapsusunun mitral yetersizlik ve panik bozukluğa katkısının araştırılması amaçlanmaktadır. Gereç ve Yöntemler: Göğüs ağrısı, çarpıntı ve halsizlik yakınması nedeniyle değerlendirlen ve sonuçta anteriyor mitral kapak prolapsusu ve non kardiyak göğüs ağrısı tanısı konulan 96 hasta panik bozukluk açısından araştırıldı. Bulgular: Mitral kapak prolapsusu olan 96 hastadan (ortalama yaş 40±8) 46'sında (%48) panik bozukluk ve 32'sinde (%33) mitral yetersizlik saptandı. Hastaların çoğunluğu (%53) kadındı ve mitral yetersizlikli 32 hastanın 22'sinde (%69) panik bozukluk vardı. Panik bozukluk saptanan hastaların %48'inde mitral yetersizlik saptandı. Mitral yetersizlikle panik bozukluk arasında istatistiksel olarak önemli korelasyon saptandı (p=0,004). Sonuç: Bu çalışmanın sonuçları anteriyor mitral kapak prolapsusunun mitral yetersizlik ve panik bozuklukla muhtemel birlikteliğini ortaya koymaktadır. Panik bozukluk ve mitral kapak prolapsusu birliktelik oluşturmakta ve bu durum daha geniş çaplı ileri çalışmalarla desteklenmelidir.

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Section: Discussionmentioning

confidence: 72%

Section: Methodsmentioning

confidence: 99%

Anterior Mitral Valve Prolapse Contributes to Mitral Regurgitation and Panic Disorder

Ulusoy¹

2012

JIUMF

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“…7 A control group of "normal" subjects was included in 11 studies (Table 2), with an important division occurring in these studies. In 7 of them, the control group consisted of hospital employees 13,47,50,64 or volunteers from the community, 49,59,61 a fact that can be considered another important selection bias. In 4 of these studies, a higher prevalence of MVP was detected in the case group.…”

Section: Prevalence Of Mitral Valve Prolapse In Patients With Panic Dmentioning

confidence: 99%

“…34,[51][52][53][54][55][56][57][58][59][60][61][62][63][64] This wide variability can be explained by different factors. As an example, not all studies used homogeneous samples; this was the case for the study by Kathol et al, 51 who included patients with other anxiety disorders, and for the studies by Pariser et al 12 and Carney et al, 45 who included patients with major depression and panic attacks.…”

Section: Prevalence Of Mitral Valve Prolapse In Patients With Panic Dmentioning

confidence: 99%

Does the Association Between Mitral Valve Prolapse and Panic Disorder Really Exist?

Filho¹,

Maciel²,

Martín‐Santos³

et al. 2008

Prim. Care Companion J. Clin. Psychiatry

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“…Dois avaliaram a associação entre as duas condições em ambas as direções, por isso também estão incluídos na tabela 4 (Hickey et al, 1983) e na tabela 5 (Tamam et al, 2000).…”

Section: Prevalência De Transtorno De Pânico Em Pacientes Com Pvmunclassified

Espectro do transtorno de ansiedade social: estudo de suas comorbidades psiquiátricas e associação com o prolapso de valva mitral

Filho¹

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The assessment of relationship between mitral valve prolapse and panic disorder

Cited by 5 publications

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Anterior Mitral Valve Prolapse Contributes to Mitral Regurgitation and Panic Disorder

Anterior Mitral Valve Prolapse Contributes to Mitral Regurgitation and Panic Disorder

Does the Association Between Mitral Valve Prolapse and Panic Disorder Really Exist?

Espectro do transtorno de ansiedade social: estudo de suas comorbidades psiquiátricas e associação com o prolapso de valva mitral

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