The Assessment of Irradiated Bladder Carcinoma Using Dynamic Contrast-enhanced MR Imaging

Dobson, M J; Carrington, Bernadette M; Collins, Christopher G.; Ryder, W. David J.; Read, G.; Hutchinson, C.E.; Hawnaur, J.M.

doi:10.1053/crad.2000.0560

Cited by 38 publications

(13 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, there may be a future for MRI in these patients with the right MR protocol. Previously, difficulties in distinguishing residual cancer from changes like inflammation and fibrosis after TURB have been reported [22] [23]. Our findings are in accordance.…”

Section: Discussionsupporting

confidence: 92%

MRI of the Bladder in Patients Suspected of Bladder Tumors

Gandrup¹,

Nordling²,

Thomsen³

2014

OJRad

View full text Add to dashboard Cite

Objective: To prospectively evaluate the use of MRI for the detecting of bladder tumors and the Tstage using T2W, T1W and diffusion-weighted images (DWI). Material and methods: Twenty-eight consecutive patients (21 men, 7 women; age range, 20 -82 years; mean age, 62.8 years) suspected of bladder tumors underwent MRI, flexible cystoscopy and transurethral resection (TURB). The presence of bladder tumor was confirmed by histopathology in 21 patients; 18 patients had pTa, one pT1 and two pT2. The images were reviewed by two uroradiologists. They assigned the presence of a bladder tumor and whether the tumor was non-muscle invasive (Ta and T1) or muscleinvasive (T2, T3 or T4). Results: Compared to the histopathological results, the accuracy for identifying a bladder tumor was 60.7% and 53.7% for reviewer A and B, respectively. The sensitivity and specificity were 66.7%/61.9% and 57.1%/42.9%. Positive predictive values were 82.6%/ 76.5%. The overall staging was correct in 47.6%/52.5%, but improved on stage-by-stage up to 50%/66.7%. The agreement between the reviewers was moderate in the detecting, staging and location of the tumor (Kappa = 0.47 -0.57). Conclusion: A simple MRI using no contrast media, but DWI, cannot replace flexible cystoscopy in the detection of new or recurrent bladder tumors.

show abstract

Section: Discussionsupporting

confidence: 92%

MRI of the Bladder in Patients Suspected of Bladder Tumors

Gandrup¹,

Nordling²,

Thomsen³

2014

OJRad

View full text Add to dashboard Cite

show abstract

“…A variety of studies have looked at the use of dynamic contrast-enhanced MRI to differentiate between tumour, oedema and fi brosis. One such study found that using a single-slice technique, with slices every 8 s, that an enhancement ratio of 1.54 greater than baseline at 80s was discriminatory for tumour (Dobson et al 2001 ).…”

Section: Radiotherapymentioning

confidence: 99%

Female Pelvis: Genital Organs

Forstner

Cunha²

2015

Imaging of Complications and Toxicity Following Tumor Therapy

View full text Add to dashboard Cite

Medical Radiology-Diagnostic Imaging is a unique series that aims to document the most innovative technologies in all fi elds within diagnostic imaging and interventional radiology, thereby informing the physician in practice of the latest advances in diagnostic imaging and percutaneous imageguided minimally invasive procedures. Th e contents are intended to cover all organs, and all modern imaging techniques and image-guided treatment modalities, with special emphasis on applications in clinical practice. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. Medical Radiology -Radiation Oncology is a unique series that aims to document the most innovative technologies in all fi elds within radiology, thereby informing the physician in practice of the latest advances in diagnostic and treatment techniques. Th e contents range from contemporary statements relating to management for various disease sites to explanations of the newest techniques for tumor identifi cation and of mechanisms for the enhancement of radiation eff ects, with the emphasis on maximizing cure and minimizing complications. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. AbstractA precise knowledge of antineoplastic drugs is an indispensable basis for the care of patients with cancer. The mechanisms of action and resistance, cross-resistance patterns, pharmacodynamics and pharmacokinetics, pharmacological interaction, and last but not least potential adverse effects should be part of this knowledge. As contemporary cancer care requires interdisciplinary and multiprofessional structures, the radiologist is an important a...

show abstract

“…We suggest that MRI is the most promising technique, and has the potential to assist in bladder-sparing protocols. Comparable to CT scanning, the conventional T2-WI and dynamic enhancement images still present difficulties in distinguishing the residual tumor tissues and the bladder wall thickening, as well as inflammation and fibrotic changes, especially after TUR therapy several weeks after cessation of therapy [55][56][57]. A recent studies attempting to evaluate the DWI application role in the follow-up of non-muscle invasive urinary bladder carcinoma after transurethral resection concluded that DW-MRI has a high reliability in differentiating post-TUR inflammatory changes from bladder tumors recurrence, which is similar to that of cystoscopy [58].…”

Section: Therapeutic Response Evaluation and Postresection Follow Upmentioning

confidence: 99%

Urinary Bladder Cancer: The Current and Potential Role of MR Imaging in Non-Distant Metastatic Lesions

Wang¹,

Guo²,

Zhou³

et al. 2013

JCT

View full text Add to dashboard Cite

Urinary bladder cancer is the second most common genitourinary malignancy in Westernized countries. A number of emerging imaging techniques have recently been reported in the literature for use in imaging bladder cancer. While the explicit application of MR imaging in bladder cancer especially in non-distant bladder cancer or bladder cancer localized in pelvic remains uncertain and awaits a thorough evaluation. Therefore, this article aims to make a systematic review of previous literature and provide a complete assessment of the value of MR as an evolving imaging tool in localized urinary bladder cancer application. Studies were conducted by searching the MEDLINE and PubMed databases up to 2012 using both medical subject heading (Mesh) and a free text method like "urinary bladder cancer", "magnetic resonance imaging" or "MRI", "diffusion weighted imaging" or "DWI". About 53 articles were selected and analyzed which were considered to be associated with the objective of this systematic review ( Table 1). Results showed that MRI especially the newer functional imaging technique like DWI may has a great potential role in localized bladder cancer like early detection, staging, evaluation of tumor aggressiveness and therapeutic responsiveness of patients in the assessment of urinary bladder cancer and so forth. Newer MRI has already proceeded promising results in bladder cancer application; and the explicit role of newer MRI in bladder cancer patients still needs further research and awaits to be thoroughly evaluated.

show abstract

The Assessment of Irradiated Bladder Carcinoma Using Dynamic Contrast-enhanced MR Imaging

Cited by 38 publications

References 11 publications

MRI of the Bladder in Patients Suspected of Bladder Tumors

MRI of the Bladder in Patients Suspected of Bladder Tumors

Female Pelvis: Genital Organs

Urinary Bladder Cancer: The Current and Potential Role of MR Imaging in Non-Distant Metastatic Lesions

Contact Info

Product

Resources

About