Earth's long-term climate has been profoundly influenced by the episodic assembly and breakup of supercontinents at intervals of ca. 500 m.y. This reflects the cycle's impact on global sea level and atmospheric CO 2 (and other greenhouse gases), the levels of which have fluctuated in response to variations in input from volcanism and removal (as carbonate) by the chemical weathering of silicate minerals. Supercontinent amalgamation tends to coincide with climatic cooling due to drawdown of atmospheric CO 2 through enhanced weathering of the orogens of supercontinent assembly and a thermally uplifted supercontinent. Conversely, breakup tends to coincide with increased atmospheric CO 2 and global warming as the dispersing continental fragments cool and subside, and weathering decreases as sea level rises. Supercontinents may also influence global climate through their causal connection to mantle plumes and large igneous provinces (LIPs) linked to their breakup. LIPs may amplify the warming trend of breakup by releasing greenhouse gases or may cause cooling and glaciation through sulfate aerosol release and drawdown of CO 2 through the chemical weathering of LIP basalts. Hence, Earth's long-term climatic trends likely reflect the cycle's influence on sea level, as evidenced by Pangea, whereas its influence on LIP volcanism may have orchestrated between Earth's various climatic states. K E Y W O R D S atmospheric CO 2 , climate, large igneous provinces, sea level, supercontinent cycle This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.