The geological sources of obsidian in the Red Sea region provide the raw material used for the production of obsidian artefacts found in prehistoric sites on both sides of the Red Sea, as far afield as Egypt, the Persian Gulf and Mesopotamia. This paper presents the chemical characterization of five obsidian geological samples and 20 prehistoric artefacts from a systematically excavated Neolithic settlement in highland Yemen. The major element concentrations were determined by SEM-EDS analysis and the trace element concentrations were analysed by the LA-ICP-MS method, an almost non-destructive technique capable of chemically characterizing the volcanic glass. A comparison of archaeological and geological determinations allows the provenance of the obsidian used for the Neolithic artefacts to be traced to definite sources in the volcanic district of the central Yemen Plateau.exploitation and use has just begun to take shape, not only in the above-mentioned areas but throughout the Red Sea Rift region.Researchers studying obsidian finds from archaeological contexts, and identifying the sources of obsidian employed for artefacts, can develop and test models concerning prehistoric interactions, access to resources, and trade. The considerable number of potential obsidian sources, combined with the scarcity of work aimed at the characterization of outcrops in the Red Sea Rift region, have often made it difficult to determine the provenance of obsidian finds from archaeological sites on both sides of the Red Sea, as far afield as Egypt (e.g., Bavay et al. 2000), the Persian Gulf and Mesopotamia. Previous studies by Zarins (1989) and Francaviglia (1985 1990a,b; demonstrated the geochemical and geological difficulties of establishing the precise provenance of a number of obsidian archaeological finds from this general region (for early reviews, see also Overstreet et al. 1988, 373-91; Overstreet and Grolier 1988, 465-6; Overstreet and Grolier 1996, 350, 386-8). More recently, continuing work by L. Khalidi and colleagues as part of the VAPOR project Lewis et al. 2010) has provided an important contribution to the knowledge of the obsidian sources in the Yemen highlands on the basis of LA-ICP-MS analyses.Among the different analytical techniques, the LA-ICP-MS method is particularly valuable for the compositional characterization of archaeological obsidian, because it combines microdestructivity with the capacity for analysing a great number of trace and rare earth elements with high sensitivity in a very short time. These characteristics make LA-ICP-MS a very powerful tool for the characterization and provenance determination of archaeological specimens (Gratuze 1999;Bavay et al. 2000;Carter et al. 2006;Barca et al. 2007;Giussani et al. 2009;Khalidi et al. 2010).In order to expand the geochemical database of obsidian sources and compositions for the Red Sea region (Francaviglia 1990b;Khalidi et al. 2010), in the present study we report the results of analyses jointly carried out on geological samples and archaeological s...