The Arabidopsis LATERAL ORGAN BOUNDARIES-Domain Gene ASYMMETRIC LEAVES2 Functions in the Repression of KNOX Gene Expression and in Adaxial-Abaxial Patterning

Lin, Wan-ching; Shuai, Bin; Springer, Patricia S.

doi:10.1105/tpc.014969

Cited by 264 publications

(312 citation statements)

References 41 publications

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“…LBD genes are suggested to be involved in developmental processes, including leaf polarity establishment (Lin et al, 2003;Xu et al, 2003) and lateral root formation (Inukai et al, 2005;Liu et al, 2005;Okushima et al, 2007). Recent results also suggest some LBDs be involved in auxin signaling (Lin et al, 2003;Inukai et al, 2005;Taramino et al, 2007;Mangeon et al, 2011). The USP protein family has been identified and studied in bacteria, but its biochemical role is not yet fully understood.…”

Section: Resultsmentioning

confidence: 99%

Reactive Oxygen Species-Driven Transcription in Arabidopsis under Oxygen Deprivation

et al. 2012

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Reactive oxygen species (ROS) play an important role as triggers of gene expression during biotic and abiotic stresses, among which is low oxygen (O 2 ). Previous studies have shown that ROS regulation under low O 2 is driven by a RHO-like GTPase that allows tight control of hydrogen peroxide (H 2 O 2 ) production. H 2 O 2 is thought to regulate the expression of heat shock proteins, in a mechanism that is common to both O 2 deprivation and to heat stress. In this work, we used publicly available Arabidopsis (Arabidopsis thaliana) microarray datasets related to ROS and O 2 deprivation to define transcriptome convergence pattern. Our results show that although Arabidopsis response to anoxic and hypoxic treatments share a common core of genes related to the anaerobic metabolism, they differ in terms of ROS-related gene response. We propose that H 2 O 2 production under O 2 deprivation is a trait present in a very early phase of anoxia, and that ROS are needed for the regulation of a set of genes belonging to the heat shock protein and ROS-mediated groups. This mechanism, likely not regulated via the N-end rule pathway for O 2 sensing, is probably mediated by a NADPH oxidase and it is involved in plant tolerance to the stress.

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Section: Resultsmentioning

confidence: 99%

Reactive Oxygen Species-Driven Transcription in Arabidopsis under Oxygen Deprivation

et al. 2012

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“…Members of this gene family can be divided into different classes and subtypes, which are involved in distinct aspects of plant development (Majer and Hochholdinger, 2011). Most LBD genes studied thus far are involved in aboveground development, including adaxial-abaxial patterning of Arabidopsis leaves (Lin et al, 2003), proximal-distal patterning in Arabidopsis petals (Chalfun et al, 2005), embryo sac and leaf development in maize (Evans, 2007), leaf expansion in Arabidopsis (Iwakawa et al, 2007), and glume formation in rice (Li et al, 2008). However, it has also been demonstrated that LBD genes are involved in different aspects of root formation, including lateral root formation in Arabidopsis (Okushima et al, 2007), shootborne root formation in rice (Inukai et al, 2005;Liu et al, 2005), and shoot-borne and seminal root initiation in maize (Taramino et al, 2007).…”

Section: Rtcs-dependent Regulation Of Lob Domain Genes and Transcriptmentioning

confidence: 99%

Comparative Transcriptome Profiling of Maize Coleoptilar Nodes during Shoot-Borne Root Initiation

et al. 2013

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Maize (Zea mays) develops an extensive shoot-borne root system to secure water and nutrient uptake and to provide anchorage in the soil. In this study, early coleoptilar node (first shoot node) development was subjected to a detailed morphological and histological analysis. Subsequently, microarray profiling via hybridization of oligonucleotide microarrays representing transcripts of 31,355 unique maize genes at three early stages of coleoptilar node development was performed. These pairwise comparisons of wild-type versus mutant rootless concerning crown and seminal roots (rtcs) coleoptilar nodes that do not initiate shoot-borne roots revealed 828 unique transcripts that displayed RTCS-dependent expression. A stage-specific functional analysis revealed overrepresentation of "cell wall," "stress," and "development"-related transcripts among the differentially expressed genes. Differential expression of a subset of 15 of 828 genes identified by these microarray experiments was independently confirmed by quantitative real-time-polymerase chain reaction. In silico promoter analyses revealed that 100 differentially expressed genes contained at least one LATERAL ORGAN BOUNDARIES domain (LBD) motif within 1 kb upstream of the ATG start codon. Electrophoretic mobility shift assay experiments demonstrated RTCS binding for four of these promoter sequences, supporting the notion that differentially accumulated genes containing LBD motifs are likely direct downstream targets of RTCS.

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“…Members of the CLASS III HOMEODOMAIN-LEUCINE ZIPPER (HD-ZIPIII) family, which in Arabidopsis thaliana includes PHABULOSA (PHB), PHAVOLUTA, and REVOLUTA (REV), specify adaxial cell fate (McConnell et al, 2001;Emery et al, 2003;Juarez et al, 2004). In addition, the Myb domain transcription factor ASYMMETRIC LEAVES1 (AS1) promotes adaxial identity in complex with the LATERAL ORGAN BOUNDARIES domain transcription factor AS2 (Lin et al, 2003;Husbands et al, 2007;Iwakawa et al, 2007). By contrast, members of the KANADI (KAN) and YABBY (YAB) gene families, along with AUXIN RESPONSE FACTOR3 (ARF3) and ARF4, contribute to the specification of abaxial cell fate (Siegfried et al, 1999;Eshed et al, 2001;Kerstetter et al, 2001;Pekker et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

The ASYMMETRIC LEAVES Complex Employs Multiple Modes of Regulation to Affect Adaxial-Abaxial Patterning and Leaf Complexity

et al. 2015

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Flattened leaf architecture is not a default state but depends on positional information to precisely coordinate patterns of cell division in the growing primordium. This information is provided, in part, by the boundary between the adaxial (top) and abaxial (bottom) domains of the leaf, which are specified via an intricate gene regulatory network whose precise circuitry remains poorly defined. Here, we examined the contribution of the ASYMMETRIC LEAVES (AS) pathway to adaxial-abaxial patterning in Arabidopsis thaliana and demonstrate that AS1-AS2 affects this process via multiple, distinct regulatory mechanisms. AS1-AS2 uses Polycomb-dependent and -independent mechanisms to directly repress the abaxial determinants MIR166A, YABBY5, and AUXIN RESPONSE FACTOR3 (ARF3), as well as a nonrepressive mechanism in the regulation of the adaxial determinant TAS3A. These regulatory interactions, together with data from prior studies, lead to a model in which the sequential polarization of determinants, including AS1-AS2, explains the establishment and maintenance of adaxial-abaxial leaf polarity. Moreover, our analyses show that the shared repression of ARF3 by the AS and trans-acting small interfering RNA (ta-siRNA) pathways intersects with additional AS1-AS2 targets to affect multiple nodes in leaf development, impacting polarity as well as leaf complexity. These data illustrate the surprisingly multifaceted contribution of AS1-AS2 to leaf development showing that, in conjunction with the ta-siRNA pathway, AS1-AS2 keeps the Arabidopsis leaf both flat and simple.

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The Arabidopsis LATERAL ORGAN BOUNDARIES-Domain Gene ASYMMETRIC LEAVES2 Functions in the Repression of KNOX Gene Expression and in Adaxial-Abaxial Patterning

Cited by 264 publications

References 41 publications

Reactive Oxygen Species-Driven Transcription in Arabidopsis under Oxygen Deprivation

Reactive Oxygen Species-Driven Transcription in Arabidopsis under Oxygen Deprivation

Comparative Transcriptome Profiling of Maize Coleoptilar Nodes during Shoot-Borne Root Initiation

The ASYMMETRIC LEAVES Complex Employs Multiple Modes of Regulation to Affect Adaxial-Abaxial Patterning and Leaf Complexity

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