“…In plants, Ca 2+ binding EF-hand proteins, including a glutamate dehydrogenase, a family of MCF ATP/P i transporters (APC1-3), and two alternative NAD(P)H dehydrogenases (NDB1 and NDB2), localize to mitochondria and show Ca 2+ -dependent activity (although the latter are regulated by Ca 2+ from the intermembrane space side of the inner mitochondrial membrane; Møller et al, 1981;Rasmusson and Møller, 1991;Turano et al, 1997;Geisler et al, 2007;Stael et al, 2011;Monné et al, 2015). Furthermore, the EF-hand protein LETM1 and the calmodulin-like protein CML30 have recently been found to be localized in mitochondria, and additional proteins with Ca 2+ binding motifs have been detected in proteomic data sets of plant mitochondria (Chigri et al, 2012;Zhang et al, 2012;Salvato et al, 2014). Moreover, there is evidence for Ca 2+ dependence of mitochondrial permeability transition, protein import, and respiration in plants (Miernyk et al, 1987;Arpagaus et al, 2002;Kuhn et al, 2009;Manzoor et al, 2012).…”