The application of ultrasound for skin and appendage regeneration: A comprehensive review

Abstract

<p>Ultrasound, an exogenous physical stimulus, has important application prospects in the field of regenerative medicine, especially in skin regeneration, due to its safety, controllability, and deep penetration depth. This review examines the potential of ultrasound therapy in promoting skin regeneration by exploring its effects on skin cells, mechanisms of action in regeneration, and responsive materials. With its deep tissue penetration and excellent biocompatibility, ultrasound presents an attractive option for enhancing wound healing and skin regeneration. By discussing current challenges and future prospects, this review offers insights to guide the development of innovative ultrasound-based approaches for clinical wound treatment.</p>