The Application of Ultrasonic Energy to the Extraction of Belladonna Leaf U. S. P.**Department of Pharmacy and Pharmaceutical Chemistry, College of Pharmacy, University of Nebraska, Lincoln

Wray, Paul E.; Small, LaVerne D.

doi:10.1002/jps.3030471118

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1969

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Cited by 10 publications

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“…This explains the relatively low yield of alkaloids obtained in certain studies. One should note also that ultrasonic action causes no detectable degradation of the active alkaloids (9, 10).…”

Section: Resultsmentioning

confidence: 99%

“…During the extraction of alkaloids from Atropa belladonna, Wray and Small (10) observed that the insonation of a maceration mixture of solvents and ground drug for 20 minutes produced the same yield of alkaloids as a conventional maceration of 8 hours when both were followed by Soxhlet extraction. Bose, Sen, and Ray (11) have reported that the maceration time for the complete extraction of alkaloids from roots of Journal of Pharmaceutical Sciences applied during the maceration of the drug was studied employing the three generators previously listed.…”

Section: Number Of Investigators Have Demonstratedmentioning

confidence: 96%

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