The application of the inexpensive and synthetically simple electrocatalyst CuFe-MoC@NG in immunosensors

Abstract

In this study, we used inexpensive and synthetic simple electrocatalysts replacement conventional precious metal materials to reduce hydrogen peroxide (H2O2). We first time developed N-doped graphene-coated CuFe@MoC using one-step calcination...

Electrochemistry/Photoelectrochemistry-Based Immunosensing and Aptasensing of Carcinoembryonic Antigen

“…Detection Technique Linear Range (pg mL −1 ) Detection Limit (pg mL −1 ) Reference MoS 2 -PBNCs DPV 5-10,000 0.54 [25] AuNPs/BSNa-CNC-PPy SWV 0.001-200,000 0.00006 [26] AuNPs/CNOs/SWCNTs/CS SWV 0.1-400,000 0.1 [27] AuNPs/PB-PEDOT DPV 50-40,000 10 [28] CPS@PANI@Au DPV 6-12,000 1.56 [29] CuFe-MoC@NG@PDA i-t 0.01-80,000 0.003 [30] AuNPs@ZrHCF@Fe 3 O 4 SWV 0.5-50,000 0.15 [31] Au/PDA/Au-PB/CNT DPV 5-50,000 3.3 [32] CNTs/rGO/Ag@BSA/PEDOT LSV 2-50,000 0.1 [33] Ag/MoS 2 /rGO i-t 0.01-100,000 0.0016 [34] Au/γ-PGA-DA@CS EIS 0.02-20,000 0.01 [35] HMSNs-Cu 2+ @HA i-t 0.01-40,000 0.0035 [36] PBNCs, Prussian blue nanocubes; BSNa, sodium benzenesulfonate; CNC, cellulose nanocrystalline; PPy, polypyrrole; CNOs, carbon nanoonions; SWCNTs, single-walled carbon nanotubes; CS, chitosan; PEDOT, poly(3,4-ethylenedioxythiophene); CPS, carboxy-functionalized polystyrene spheres; PANI, polyaniline; NG, N-doped graphene; PDA, polydopamine; ZrHCF, zirconium hexacyanoferrate; rGO, reduced graphene oxide; BSA, bovine serum albumin; γ-PGA, poly(γ-glutamic acid); HMSNs, hollow mesoporous silica nanoparticles; HA, hyaluronic acid.…”

“…Since the intrinsic features of immune proteins limit their applications in immunoassays as redox partners, the combination of secondary antibodies (Ab 2 ) and signal amplification labels has been extensively applied to most immunosensors for the monitoring of current intensities from electroactive probes (e.g., H 2 O 2 and ferrocene) [37,38]. As a result, it is highly desirable to synthesize effective label materials with excellent catalytic performances in the development of sensitive immunosensing platforms [30,39,40]. Based on this, copper ion-loaded cubic Au@Pt dendritic nanomaterial-functionalized nitrogen-doped graphene (Au@Pt DNs/NG/Cu 2+ ) with large surface areas and remarkable adsorption capabilities were first prepared and served as label units to capture numerous Ab 2 (Figure 3) [41].…”