The Application of the Combined Drug Polidex in the Therapy of Otitis Externa of Various Bacteriological Etiology

Сапова, К. И.; Рязанцев, С. В.

doi:10.21518/2079-701x-2017-16-92-95

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…Утрата плоского эпителия с латеральной поверхности БП приводит к обнажению ее фиброзного слоя. В условиях постоянного воспаления заживление происходит путем продукции незрелой грануляционной ткани, покрывающей деэпидермизированную БП [4]. Грануляции могут диффузно покрывать всю БП или быть локализованы в одном квадранте при интактных других.…”

Section: Rossiiskaya Otorinolaringologiyaunclassified

Structure features of the temporal bone in patients with acquired post-inflammatory atresia of the external auditory canal

Диаб¹,

Дайхес²,

Кондратчиков³

et al. 2020

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Objective: Comparative analysis of the structure of the external auditory canal (EAC) according to computed tomography (CT) scans of the temporal bones in patients with acquired post-inflammatory atresia of the EAC and patients with safe chronic suppurative otitis media (SCSOM) without atresia. Patients and methods: 42 patients (43 ears) with acquired post-inflammatory atresia of the EAC and 11 patients (22 ears) with bilateral SCSOM without acquired atresia were included in the study. Based on the original axial СT images and multi-planar reformation images were measured: thickness of the anterior wall in bony part of EAC; anterior tympanomeatal angle and the distance from the lateral process of the malleus to the anterior wall of an EAC; lumen of the EAC in front of the tympanic sulcus. Results: The lumen of the bone part of the EAC in patients with acquired post-inflammatory atresia is 17,0% less than in patients with SCSOM without atresia; patients with acquired post-inflammatory atresia have a more acute anterior tympanomeatal angle (33° versus 68°) than patients with SCSOM without atresia. The thickness of the anterior wall of the EAC in the bone part in patients with acquired post-inflammatory atresia of the EAC does not statistically differ from the analogous parameter in patients with SCSOM without atresia. Conclusion: The revealed results indirectly indicate the presence of certain features of the structure of the external ear in patients with acquired post-inflammatory atresia of the EAC such as narrower anterior tympanomeatal angle and lumen of the bone part. These features of the EAC structure may contribute to the more likely development of post-inflammatory atresia development.

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Section: Rossiiskaya Otorinolaringologiyaunclassified

Structure features of the temporal bone in patients with acquired post-inflammatory atresia of the external auditory canal

Диаб¹,

Дайхес²,

Кондратчиков³

et al. 2020

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Acute otitis externa in children: causes, diagnosis, treatment, clinical report

Popadyuk

Kozlova²

2021

Medicinskij sovet

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Acute otitis externa is a common disease in the pediatric population, characterized by diffuse inflammation of the external auditory canal. Typical symptoms of acute otitis externa include otology, itching, congestion, and a feeling of fullness in the sore ear. In the case of active inflammation, the process can go to the tympanic membrane, and acute otitis media will join the external one. Primary therapy for diffuse uncomplicated acute otitis externa should include a local antimicrobial drug, without systemic antibiotic therapy. Topical therapy with antibacterial drugs in combination with anesthetics is the most rational. A clinical case of a 12-year-old patient with acute diffuse otitis externa and otitis media with effusion; acute nasopharyngitis; and adenoiditis, which was established based on anamnesis and clinical data is presented. Complex therapy was prescribed, which included local antibiotic therapy with a complex topical drug for the treatment of imperforated otitis externa and imperforated otitis media. At reexamination 5 days later, the patient demonstrated positive dynamics, pain in the left ear was eliminated. In cases of uncomplicated diffuse otitis externa, as well as in cases of its combination with otitis media with effusion, topical antibiotic therapy is a major priority. It should be borne in mind that the topical medication is more effective with the cleansing of the external auditory canal from inflammatory secretion. If it is used correctly, it would provide positive dynamics without systemic antibiotic prescription. It preserves the microbiome and mobilizes the body’s defenses. The application of complex topical antibiotic drugs can be widely recommended in pediatric practice.

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External otitis media: modern possibilities for improving the effectiveness of treatment and the quality of life of patients

Korkmazov,

Gizinger,

Kornova

et al. 2024

Medicinskij sovet

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Introduction. Polyethologicity of otitis externa with inflammation of the auricle, ear canal and outer layer of the eardrum, persistent course and high probability of recurrence necessitates improved treatment.Aim. To evaluate the effectiveness of the use and the impact on the quality of life of combined ear drops with antimicrobial and local anesthetic effects.Materials and methods. A simple randomized controlled clinical trial involved 56 people, including 25 women and 31 men aged 32 to 56 years, suffering from acute diffuse otitis externa. Clinical efficacy, recovery time and impact on quality of life were evaluated in two groups: groups 1 (n = 27), patients receiving ear drops containing choline acetate as local therapy, with group 2 (n = 29) taking a multicomponent drug containing polymyxin B sulfate 1,000,000 IU, neomycin sulfate 0.5 g (375,000 IU) and lidocaine hydrochloride in the form of ear drops. The assessment of otalgia, hearing loss and discharge from the external auditory canal was carried out on the VAS, quality of life scale using the SF-36 general questionnaires.Results and discussion. There was a positive dynamic of clinical manifestations and restoration of quality-of-life indicators in a shorter period (3rd, 5th day) with the disappearance of all the main clinical symptoms (7th day) with good tolerability and absence of side effects in the second group of patients taking the multicomponent drug.Conclusions. The use of ear drops containing a combination of topical antimicrobial drugs with an anesthetic in the complex therapy of otitis externa significantly improved the clinical symptoms and quality of life of patients.

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The Application of the Combined Drug Polidex in the Therapy of Otitis Externa of Various Bacteriological Etiology

Cited by 3 publications

References 2 publications

Structure features of the temporal bone in patients with acquired post-inflammatory atresia of the external auditory canal

Structure features of the temporal bone in patients with acquired post-inflammatory atresia of the external auditory canal

Acute otitis externa in children: causes, diagnosis, treatment, clinical report

External otitis media: modern possibilities for improving the effectiveness of treatment and the quality of life of patients

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