The application of optical coherence tomography angiography in retinal diseases

Saurabh, Kumar; Grover, Sandeep; Chalam, Kakarla V

doi:10.1016/j.survophthal.2017.05.006

Cited by 109 publications

(85 citation statements)

References 149 publications

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“…Different software algorithms are used to realize visualization and quantitative analysis such as OMAG (OCTbased optical microangiography), SSADA (split-spectrum amplitude-decorrelation angiography), or OCT-ARA (OCT angiography ratio analysis) [11,12]. A comparison of two OCTA devices with different software approaches (SSADA and OMAG) with focus on CC quantification measurements resulted in a basic agreement between measurements [13].…”

Section: Heidelberg Spectralismentioning

confidence: 99%

Optical Coherence Tomography Angiography Offers New Insights into Choriocapillaris Perfusion

Lauermann¹,

Eter²,

Alten³

2018

Ophthalmologica

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The choriocapillaris (CC) represents a fundamentally important vascular layer that is subject to physiologic changes with increasing age and that is also associated with a wide range of chorioretinal diseases. So far, information on blood flow in this specific layer has remained limited. With the advent of optical coherence tomography angiography (OCTA), new perspectives and possibilities of CC imaging have begun to evolve. This article shall review the opportunities and challenges of applying OCTA technology to the CC layer and summarize the current clinical efforts in OCTA CC imaging exemplarily in dry age-related macular degeneration and central serous chorioretinopathy.

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Section: Heidelberg Spectralismentioning

confidence: 99%

Optical Coherence Tomography Angiography Offers New Insights into Choriocapillaris Perfusion

Lauermann¹,

Eter²,

Alten³

2018

Ophthalmologica

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“…OCT‐A has also shown capillary impairment associated with intra‐retinal microvascular abnormalities, cotton wool spots or anomalous vascular loops and thus may be useful in staging disease severity . Areas of capillary non‐perfusion appear to be better delineated on OCT‐A than with fluorescein angiography or clinical examination . Capillary closure may occur in early stages of DR, worsening as DR progresses; thus measurements such as FAZ size could potentially represent biomarkers for DR progression .…”

Section: Diabetic Retinopathy (Dr)mentioning

confidence: 99%

An evidence‐based approach to the routine use of optical coherence tomography

Phu

Katalinic

et al. 2019

Clinical and Experimental Optometry

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Optical coherence tomography is an imaging technology that has revolutionised the detection, assessment and management of ocular disease. It is now a mainstream technology in clinical practice and is performed by non‐specialised personnel in some settings. This article provides a clinical perspective on the implications of that movement and describes best practice using multimodal imaging and an evidence‐based approach. Practical, illustrative guides on the interpretation of optical coherence tomography are provided for three major diseases of the ocular fundus, in which optical coherence tomography is often crucial to management: age‐related macular degeneration, diabetic retinopathy and glaucoma. Topics discussed include: cross‐sectional and longitudinal signs in ocular disease, so‐called ‘red‐green’ disease whereby clinicians rely on machine/statistical comparisons for diagnosis in managing treatment‐naïve patients, and the utility of optical coherence tomography angiography and machine learning.

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“…OCTA provide an available and noninvasive device to monitoring CNV in AMD [9,10] and other related disorders. It is helpful to image the FAZ in eyes with unexplained visual loss and can provide information of the deep retinal capillary (Figure 1).…”

Section: Applications Of Octamentioning

confidence: 99%