“…More than fifty lamellarins have been isolated, mainly from marine sponges, since the first isolation of lamellarins A–D was reported by Faulkner and Clardy (Figure ). The lamellarins possess various biological activities and are structurally complex, compared with the related natural products, ningalins, lukianols, didemnimides, dictyodendrins, polycitrins, and storniamides . Tremendous synthetic efforts have been made toward the total synthesis of lamellarins by Fürstner, Steglich, Banwell, Iwao/Ishibashi, Boger, Gupton, ,, Ruchirawat, Álvarez, Handy, Opatz, Jia, Itami/Yamaguchi, Yang, Wu/Wu, Chandrasekhar, and Michael groups.…”