The Application of Carbon Nanomaterials in Sensing, Imaging, Drug Delivery and Therapy for Gynecologic Cancers: An Overview

Abstract

Gynecologic cancers are one of the main health concerns of women throughout the world, and the early diagnosis and effective therapy of gynecologic cancers will be particularly important for the survival of female patients. As a current hotspot, carbon nanomaterials have attracted tremendous interest in tumor theranostics, and their application in gynecologic cancers has also been developed rapidly with great achievements in recent years. This Overview Article summarizes the latest progress in the application of diverse carbon nanomaterials (e.g., graphenes, carbon nanotubes, mesoporous carbon, carbon dots, etc.) and their derivatives in the sensing, imaging, drug delivery, and therapy of different gynecologic cancers. Important research contributions are highlighted in terms of the relationships among the fabrication strategies, architectural features, and action mechanisms for the diagnosis and therapy of gynecologic cancers. The current challenges and future strategies are discussed from the viewpoint of the real clinical application of carbon-based nanomedicines in gynecologic cancers. It is anticipated that this review will attract more attention toward the development and application of carbon nanomaterials for the theranostics of gynecologic cancers.

Fabrication and Characterization of Ag-Graphene Nanocomposites and Investigation of Their Cytotoxic, Antifungal and Photocatalytic Potential

“…The average size of AgNPs is calculated as ~24 nm, GNPs as ~32 nm, and (Ag) 1−x (GNPs) x nanocomposites as 34 nm. Our XRD configuration for the described nanocomposites is consistent with earlier studies [ 52 , 53 , 54 ]. The functional groups present in the (Ag) 1−x (GNPs) x nanocomposites were confirmed by exploiting an FTIR analysis to obtain the desired spectra ( Figure 3 ).…”

The utilization of nanotechnology in the female reproductive system and related disorders

“…Nanomaterials hold tremendous potential in the realm of female reproductive system diseases, with targeted therapy, early diagnosis, drug delivery systems, and tissue engineering and regenerative medicine among their future focus areas [ 9 , 83 , 181 ].…”

“…Traditionally, treatment methods for female reproductive system diseases have faced limitations in terms of suboptimal drug efficacy and severe side effects [ 9 ]. Consequently, the pursuit of more effective and precise treatment strategies assumes paramount significance.…”

Synthesis of Graphene-Based Nanocomposites for Environmental Remediation Applications: A Review

“…Graphene is a purified form of graphite that recently gained enormous popularity in the energy [ 1 , 2 , 3 ], environment [ 4 , 5 , 6 , 7 , 8 ], membranes [ 1 , 7 ], sensor [ 9 , 10 , 11 , 12 ], and biomedical fields [ 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ]. It is a sp 2 hybridized, hexagonally arranged, chain of polycyclic aromatic hydrocarbon with a honeycomb crystal lattice [ 27 ].…”