The Application of Assembly and Automation Technologies to Healthcare Products

Williams, David J.; Ratchev, Svetan; Chandra, Amit; Hirani, Hitendra

doi:10.1016/j.cirp.2006.10.001

Cited by 9 publications

(6 citation statements)

References 133 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Even though promising, several industrial and technological challenges must be faced to realize factories that are able to produce large quantities of the most interesting healthcare products, including LoC solutions [101]. The expertise needed for the design and manufacturing of LoC devices includes electronics, advanced materials, photonics, chemistry and microfluidics [90].…”

Section: Industrial and Technological Challengesmentioning

confidence: 99%

Key Research Priorities for Factories of the Future—Part I: Missions

Tolio

Copani

Terkaj

2019

Factories of the Future

View full text Add to dashboard Cite

This chapter investigates research priorities for factories of the future by adopting an approach based on mission-oriented policies to support manufacturing innovation. Missions are challenging from a scientific and technological point of view and, at the same time, are addressing problems and providing results that are understandable by common people. Missions are based on clear targets that can help mitigating grand challenges. Based on the results of the Italian Flagship Project Factories of the Future, this chapter proposes seven missions while identifying the societal impact, the technological and industrial challenges, and the barriers to be overcome. These missions cover topics such as circular economy, rapid and sustainable industrialisation, robotic assistant, factories for personalised medicine, internet of actions, factories close to the people, and turning ideas into products. The accomplishment of missions asks for the support of a proper research environment in terms of infrastructures to test and demonstrate the results to a wide public. Research infrastructures together with funding mechanisms will be better addressed in the next chapter of this book. 20.1 Mission-Oriented Research and Innovation Policies The importance of the manufacturing industry both for developed and developing countries has been assessed in several works [1-4], which highlight the need of continuous innovation to cope with societal grand challenges [5]. The results of inno-T. Tolio Director of the Italian Flagship Project "Factories of the Future", Direttore del Progetto Bandiera "La Fabbrica del Futuro",

show abstract

Section: Industrial and Technological Challengesmentioning

confidence: 99%

Key Research Priorities for Factories of the Future—Part I: Missions

Tolio

Copani

Terkaj

2019

Factories of the Future

View full text Add to dashboard Cite

show abstract

“…Systematic, robust and efficient delineation and characterization methods to assert the phenotype of cells are at the core of this. Platforms and more effective standard protocols for cell cultivation and expansion in culture and the genetic alteration of cells, if required, will make significant contributions in establishing the conditions for application of stem cells as cell therapies, in tissue engineering and in the development of new drugs (Archer and Williams, 2005;Williams et al, 2006). Once the unanswered practical questions have been resolved, the remaining principal challenge is to successfully initiate and accomplish human trials for these cell-based therapies and ultimately introduce commercially feasible therapies in the market.…”

Section: Commercial Conditions For Success: Key Enabling Technologiesmentioning

confidence: 99%

Cell therapies: realizing the potential of this new dimension to medical therapeutics

Singh

Williams

2008

J Tissue Eng Regen Med

View full text Add to dashboard Cite

Stem cells promise to treat conditions poorly served by conventional therapeutics. Cells from both embryonic and somatic tissues are being used to create cell therapies for genetic, traumatic and degenerative conditions. The current human, healthcare and fiscal costs of these conditions are significant. This review summarizes the use of stem cells for neurological and cardiac disorders and diabetes to determine the requirements for generic translational research to assist such therapies to be a reality. While there are multiple strategies in each disease area, with no clear favourite, there are clear opportunities in treatments that use a single cell type. A key requirement is to work with pluripotent progenitor cells to cultivate and differentiate a sufficiently large population of functioning cells. Challenges also arise in determining and achieving timely delivery of the correct dose of cells to where they can most effectively treat the disease and best benefit individual patients.

show abstract

“…The biomedical market is such an example where the miniaturised assemblies, zero defects constraints, high number of variants and unpredictable volumes together with the time and cost to develop, deploy and validate the assembly system reduces the application of automatic solutions [19,25]. Markets with these characteristics are exactly where there is a potential gain, both in cost and system responsiveness, of using modern automation paradigms.…”

Section: Introductionmentioning

confidence: 98%

Prospection of Methods to Support Design and Configuration of Self-Organizing Mechatronic Systems

Neves

Ferreira

Onori

et al. 2013

2013 IEEE International Conference on Systems, Man, and Cybernetics

View full text Add to dashboard Cite

There is a substantial difference between traditional industrial systems and systems resultant from emerging production paradigms in terms of both conceptualization and implementation. Backwards compatibility is fundamental in assessing the potential transitional period whereby legacy technology will operate under the conceptual framework of modern approaches. However, before this point can be reached it is necessary to further investigate, assess and quantify the behavior of modern approaches that increasingly rely in selforganization. This article's goal is to give an overview of the behavioral assessment problematic, in the context of selforganizing mechatronic systems, and provide a discussion on opportunities to explore rule-extraction techniques to better understand the influence of design and configuration on the overall system behavior. Although the discussion widely applies to almost all emerging production paradigms the Evolvable Production System paradigm is used as case to bring context and clarity to the discussion.

show abstract

The Application of Assembly and Automation Technologies to Healthcare Products

Cited by 9 publications

References 133 publications

Key Research Priorities for Factories of the Future—Part I: Missions

Key Research Priorities for Factories of the Future—Part I: Missions

Cell therapies: realizing the potential of this new dimension to medical therapeutics

Prospection of Methods to Support Design and Configuration of Self-Organizing Mechatronic Systems

Contact Info

Product

Resources

About