The application of a UHPLC system to study the formation of various chemical species by compounds undergoing efficient self-aggregation and to determine the homodimerization constants (K_DM) with values in the high range of 10⁶–10¹⁰ M⁻¹

Abstract

This work demonstrates a new concept for the use of UHPLC method for identification of the species formed by a self-aggregating compound depending on its concentration and solvent used and to determine homodimerization constants, KDM = 106–1010 M−1.