The application of a protein fraction derived fromTreponema Pallidum (reiter strain) as an antigen in the serodiagnosis of syphilis

Reiter Protein Complement Fixation Test for Syphilis

“…The only other investigation, to our knowledge, of a comparison of Reiter protein antigen with a specific test (TPI) is the work of J. H. de Bruijn of the National Institute of Public Health, Utrecht, Netherlands (16). His results with 116 syphilitic and 137 presumably nonsyphilitic serum specimens compare favorably with the results of this investigation.…”

Modern Methods in the Serological Diagnosis of Syphilis

“…and E.P.C.P. tests, aU of which are regarded by most writers as specific for treponematoses Garson, 1957, 1959 ;de Bruijn, 1957 ;Kostant and Kelcec, 1958 ;Foster, Mcol andStone, 1958, 1959 ;De Groat and Miyao, 1958 ;Miller, Boak and Carpenter, 1958 ;Wilkinson and Johnston, 1959 ;Peterson, de Haven, Wright and MiUer, 1960 ; and see also Beerman, I:«ficholas, Schamberg, Greenberg and Outhe, 1961). Of these three tests the E.P.C.P.…”

“…Three other antigenic fractions have been identified in the same organism : a heat-stable polysaccharide and two lipids, one of which is related in specificity to cardiolipin (D'Alessandro, Oddo and. Dardanoni, 1950;PucineUi, 1952;de Bruijn, 1957).…”