The apoptotic effect of ozone therapy on mitochondrial activity of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches

Yıldırım, Merve; Erkişi, Selen; Yılmaz, Hazal; Ünsal, Naz; İnaç, Elif; Tanrıver, Yıldıray; Koçak, Polen

doi:10.1016/j.jimed.2022.03.004

Journal of Interventional Medicine

2022

DOI: 10.1016/j.jimed.2022.03.004

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The apoptotic effect of ozone therapy on mitochondrial activity of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches

Merve Yıldırım

Selen Erkişi

Hazal Yılmaz

et al.

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2024

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Ozone Therapy for Breast Cancer: An Integrative Literature Review

Li,

2024

Integr Cancer Ther

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Breast cancer is the most prevalent form of cancer in women. Despite significant advances in conventional treatment, additional safer complementary treatment options are needed. Recently, ozone therapy has been considered as a type of medical adjunctive treatment that could inhibit cancer cell survival and reduce chemoresistance. However, only a few studies have been conducted on its use in breast cancer, and the optimal dosage and time of administration are unknown. Currently, preclinical studies suggest that ozone alone or in combination with chemotherapy is an effective method for inhibiting breast cancer cell growth. However, rather than investigating the effects of ozone as an antitumor therapy, current clinical trials have generally assessed its effect as an adjunctive therapy for reducing chemotherapy-induced side effects, increasing oxygen tension, normalizing blood flow, restoring blood lymphocytes more rapidly, and reducing fatigue symptoms. In this article, the use of ozone as a medical adjunctive treatment for breast cancer and its role in integrative therapy are summarized and discussed.

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Ozone Therapy for Breast Cancer: An Integrative Literature Review

Li,

2024

Integr Cancer Ther

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The apoptotic effect of ozone therapy on mitochondrial activity of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches

Cited by 1 publication

References 17 publications

Ozone Therapy for Breast Cancer: An Integrative Literature Review

Ozone Therapy for Breast Cancer: An Integrative Literature Review

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