“…With the ability of octyl gallate and heptyl gallate which can affect the mechanism of proinflammatory regulation by suppressing the NFkB pathway and COX-2 secretion, the inflammatory process could be prevented and or suppressed, so the process of proliferation, invasion, angiogenesis, and persistence of ectopic implants in endometriosis cells was not occurred. This was in line with the results of our previous studies that demonstrated the ability of gallate acid, heptyl gallate, and octyl gallate to reduce cell proliferation and increase apoptotic endometriosis cells [24,25]. Likewise, previous studies reported that the alkyl ester derivatives of gallic acid such as heptyl gallate and octyl gallate had the ability to suppress proliferation and induced apoptosis in some cancer cells [12].…”