The Antipsychotics and Sexual Functioning Questionnaire (ASFQ): Preliminary evidence for reliability and validity

Boer, Marrit K. de; Castelein, S.; Bous, J; Heuvel, Edwin R. van den; Wiersma, Durk; Schoevers, Robert A.; Knegtering, Henderikus

doi:10.1016/j.schres.2013.08.037

Cited by 25 publications

(29 citation statements)

References 21 publications

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“…It was compiled on the basis of several international instruments for monitoring the side effects of antipsychotic medications (de Boer et al . ; Day et al . ; Jordan et al .…”

Section: Methodsmentioning

confidence: 99%

“…This instrument had originally been developed in response to a multidisciplinary guideline developed recently for somatic screening and for administering lifestyle interventions for patients with SMI (van der Kellen 2010; Meijel 2015b). It was compiled on the basis of several international instruments for monitoring the side effects of antipsychotic medications (de Boer et al 2013;Day et al 1995;Jordan et al 2004;Morrison et al 2000;Van Harten 2004) and supplemented with items based on recommendations from the Dutch multidisciplinary guidelines. A draft version of the instrument was reviewed in several rounds by a Delphi study consisting of expert mental health nurses, nurse practitioners, psychiatrists, and physicians working on somatic care for psychiatric patients.…”

Section: Measurementsmentioning

confidence: 99%

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Physical health status of older adults with severe mental illness: The PHiSMI‐E cohort study

Houben

Janssen

Hendriks

et al. 2018

Int J Mental Health Nurs

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The objective was to use various somatic parameters as basis for investigating the physical health of older adults with severe mental illnesses (SMI). A cross‐sectional study design is performed by using baseline data from the Physical Health in SMI‐elderly (PHiSMI‐E) study. Data were collected using the Nursing Monitoring of Somatic Status and Lifestyle – Mental Health instrument in adults aged over 60 with SMI in a large Dutch mental health institute. Ninety‐nine elderly SMI patients were included. Somatic comorbidity (84.8%), use of somatic medication (77.7%) and polypharmacy (67.7%) were prevalent. Extrapyramidal symptoms were experienced by 51% of patients, mainly in the subgroup with psychotic disorders (75.6%). Unhealthy diet was reported in 16.2%, obesity in 27.3%, and physical inactivity in 57.6%. Fatigue (67.7%) and dry mouth (66.6%) were the commonest reported physical symptoms. Mean VAS score (scale 0–10) indicating participants’ self‐perceived physical health was 6.7 (SD ± 1.6). After division of the total patient group into tertiles based on the VAS scores, the lowest tertile was characterized by less physical activity, unhealthier diet, more use of medication, more fatigue, somnolence, and inner agitation. In conclusion, impaired physical health status was common in these older patients with SMI. Although they had more psychiatric and somatic comorbidity than adult SMI patients described in the literature, they had a healthier lifestyle. To reduce morbidity and premature mortality in these frail patients, it is essential that healthcare providers are aware of the high prevalence of somatic comorbidity and symptoms, and of their interactions with the psychiatric disorders. This study improves our understanding of differences in vulnerability factors of older patients with SMI. The (early) detection of somatic comorbidities may improve long‐term health outcomes of these patients.

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“…It was compiled on the basis of several international instruments for monitoring the side effects of antipsychotic medications (de Boer et al . ; Day et al . ; Jordan et al .…”

Section: Methodsmentioning

confidence: 99%

Section: Measurementsmentioning

confidence: 99%

Physical health status of older adults with severe mental illness: The PHiSMI‐E cohort study

Houben

Janssen

Hendriks

et al. 2018

Int J Mental Health Nurs

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“…Sexual dysfunction – including reduced libido, anorgasmia and erectile dysfunction – is common in patients taking antipsychotics and must be monitored by prescribers. One measure to use is the Antipsychotics and Sexual Function Questionnaire. Assessment of a patient with sexual dysfunction should include obtaining prolactin levels, reviewing other medications that may contribute, and ruling out potential comorbid causes.…”

Section: Specific Adverse Effectsmentioning

confidence: 99%

Management of common adverse effects of antipsychotic medications

2018

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The benefits of antipsychotic medications are sometimes obscured by their adverse effects. These effects range from relatively minor tolerability issues (e.g., mild sedation or dry mouth) to very unpleasant (e.g., constipation, akathisia, sexual dysfunction) to painful (e.g., acute dystonias) to disfiguring (e.g., weight gain, tardive dyskinesia) to life-threatening (e.g., myocarditis, agranulocytosis). Importantly, adverse effect profiles are specific to each antipsychotic medication and do not neatly fit into first- and second-generation classifications. This paper reviews management strategies for the most frequent side effects and identifies common principles intended to optimize net antipsychotic benefits. Only use antipsychotics if the indication is clear; only continue antipsychotics if a benefit is discernible. If an antipsychotic is providing substantial benefit, and the adverse effect is not life-threatening, then the first management choice is to lower the dose or adjust the dosing schedule. The next option is to change the antipsychotic; this is often reasonable unless the risk of relapse is high. In some instances, behavioral interventions can be tried. Finally, concomitant medications, though generally not desirable, are necessary in many instances and can provide considerable relief. Among concomitant medication strategies, anticholinergic medications for dystonias and parkinsonism are often effective; beta-blockers and anticholinergic medications are useful for akathisia; and metformin may lead to slight to moderate weight loss. Anticholinergic drops applied sublingually reduce sialorrhea. Usual medications are effective for constipation or dyslipidemias. The clinical utility of recently approved treatments for tardive dyskinesia, valbenazine and deutetrabenazine, is unclear.

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“…Risperidone and amisulpride are medications that poorly pass the blood brain barrier and have a poor central-to-peripheral ratio. As a result, they are associated with a significant increase in prolactin levels [8,42]. In order to rank the agents, the results by Leucht et al were used [1], complemented with results of two reviews [9,10].…”

Section: Menstrual Disorder (Women Only) Q: How Acceptable Is It If Ymentioning

confidence: 99%

The Personal Antipsychotic Choice Index

et al. 2017

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The Antipsychotics and Sexual Functioning Questionnaire (ASFQ): Preliminary evidence for reliability and validity

Cited by 25 publications

References 21 publications

Physical health status of older adults with severe mental illness: The PHiSMI‐E cohort study

Physical health status of older adults with severe mental illness: The PHiSMI‐E cohort study

Management of common adverse effects of antipsychotic medications

The Personal Antipsychotic Choice Index

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