The antiplaque effect of herbal mouthwash in comparison to chlorhexidine in human gingival disease: a randomized placebo controlled clinical trial

Bhat, Nagesh; Mitra, Ruchi; Oza, Swapnil; Mantu, Vinayak Kumar; Bishnoi, Sharda; Gohil, Mandeepsinh; Gupta, Rupam

doi:10.1515/jcim-2014-0002

Cited by 26 publications

(34 citation statements)

References 22 publications

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“…There are numerous toothpastes and rinses with different compositions on the market. Toothpastes contain, e.g., fluorine, triclosan and xylitol, whereas rinses contain chlorhexidine, cetylpyridinium, alcohol, essential oils and herbal components [ 10 , 11 , 12 , 13 , 14 , 15 , 16 ]. Natural ingredients are gaining in popularity as components of toothpastes and rinses.…”

Section: Introductionmentioning

confidence: 99%

The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures

et al. 2017

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The study was based on the use of a toothpaste with antiphlogistic activity, containing Australian Melaleuca alternifolia oil (tea tree oil—TTO) and ethanolic extract of Polish propolis (EEP). Fifty-one patients with varying conditions of the gingiva were divided into two groups. The study group received the toothpaste with TTO and EEP, while the control group received the same toothpaste but without TTO and EEP. Approximal plaque index (API), simplified oral hygiene index (OHI-s) and modified sulcus bleeding index (mSBI) were assessed in three subsequent stages. During each examination, swabs were employed for microbiological inoculation. During the period of use of toothpastes with TTO and EEP, a significant reduction of the API was observed, as assessed upon the control visit after 7 days and after 28 days, compared to baseline. A statistically significant reduction of mSBI was observed after 7 and 28 days of using the toothpaste with TTO and EEP, as compared to the value upon the initial visit. Statistically significant differences in the OHI-s value were observed in the study group, which was using the active toothpaste. The use of a toothpaste containing TTO and EEP helps to maintain microbiome balance. The observed stabilisation of bacterial microflora confirms the beneficial activity of toothpaste containing EEP and TTO compared to the control group, where the lack of these substances contributed to the emergence of qualitative and quantitative changes in oral microbiome.

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Section: Introductionmentioning

confidence: 99%

The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures

et al. 2017

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“…Conventional anticariogenic agents are although numerous, majority of them are known to have side effects such as multiple drug resistance [1]. Herbal medicine has gained importance in the field of dentistry due to its minimal adverse effects on the oral tissue and is, as effective as the conventional anticariogenic agents [7]. World Health Organisation (WHO) pro posed that, any medicinal herb has to go through various scientific studies to establish the potential for its therapeutic use [8].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Effects of Garcinia Mangostana on Cariogenic Microorganisms

Janardhanan

Mahendra

Girija

et al. 2017

JCDR

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“…The effect of chlorhexidine and Salvadora persica containing mouthwashes on the dental plaque and gingival condition of otherwise healthy patientsis examined and compared in many studies ( 22 , 28 , 29 , 30 ). Actually, anti-plaque and anti-inflammatory effects of Persica and chlorhexidine can be the reason for promoting the patients’ condition of teeth and gingiva and consequently promoting oral health status of the children receiving chemotherapy in the present study.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the additive effect of Persica and chlorhexidine mouthwashes on oral health status of children receiving chemotherapy for their hematomalignancy: A randomized clinical trial

Bahrololoomi

Sadat-Hashemi

Hassan-Akhavan-Karbassi

et al. 2020

J Clin Exp Dent

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Background No definitive protocol has been introduced for treatment or prevention of chemotherapy induced mucositis. The aim of this study was to assess the additive effect of Persica and chlorhexidine on chemotherapy induced mucositis of children with hematomalignancies. Material and Methods This randomized clinical trial was performed on 44 children aged 6 to 12 years who were under a similar maintenance chemotherapy protocol for their hematomalignancies. The clinician instructed oral hygiene cares to the patients and their parents and the severity of the mucositis and oral health status of patients were evaluated according to Oral Assessment Guide index. Then, the patients were randomly assigned to one of two experimental groups and were instructed to rinse either with Persica oral drops or normal saline, twice a day for two weeks. Subsequently, the patients in both groups were educated to rinse with chlorhexidine for 30 seconds and avoid eating for an hour. Second and third oral examinations were performed on the 8th and 15th day using the same questionnaire. Results Comparing severity of mucositis and oral health status of patients did not show any significant difference between treatment groups in either of examination sessions ( p >0.05). However, both treatment groups showed statistically significant oral health improvement, in terms of mucositis, plaque accumulation and gingival condition, in 14 days following mouthrinses administration ( p <0.05). Conclusions Both mouth-rinse combinations were effective on mucositis, plaque and gingival status of children receiving chemotherapy. However, Persica does not seem to pose additional effect on chlorhexidine in decreasing severity of chemotherapy induced mucositis. Key words: Mucositis, chemotherapy, children, chlorhexidine, Persica.

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The antiplaque effect of herbal mouthwash in comparison to chlorhexidine in human gingival disease: a randomized placebo controlled clinical trial

Cited by 26 publications

References 22 publications

The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures

The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures

Antimicrobial Effects of Garcinia Mangostana on Cariogenic Microorganisms

Evaluating the additive effect of Persica and chlorhexidine mouthwashes on oral health status of children receiving chemotherapy for their hematomalignancy: A randomized clinical trial

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