The Antidiabetic and Antioxidant Activity of Coccinea Grandis Voigt Stem Extract in Streptozotocin Induced Diabetic Rats

Momin, Yasmin H.; Yeligar, Veerendra C.

doi:10.22270/jddt.v9i4-a.3438

Cited by 5 publications

(2 citation statements)

References 9 publications

(9 reference statements)

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“…Em outros estudos (Kim & Kim 2012;Ahangarpour et al 2017;Momin & Yeligar 2019), que também empregaram plantas medicinais como tratamentos, os autores observaram redução nos níveis de triglicerídeos. Esses estudos sugerem que a atividade antioxidante dos extratos pode ser responsável pelos resultados encontrados.…”

Section: Resultsunclassified

Propriedades antidiabéticas de cerveja enriquecida com Baccharis dracunculifolia

Silva¹,

Silva²,

Malfatti³

et al. 2022

RSD

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Objetivo: O objetivo do presente trabalho foi verificar as respostas metabólicas de uma cerveja com adição Baccharis dracunculifolia em pacientes diabéticos. Metodologia: Foram participantes do estudo, 06 indivíduos voluntários com diagnóstico de diabetes mellitus tipo 2. Ocorreu a análise bioquímica e avaliação física antes e após 30 dias de tratamento com a cerveja com B. dracunculifolia. Resultados: Após receberem o tratamento com a cerveja com B. dracunculifolia, os pacientes apresentaram diminuição dos níveis de creatinina (23%). A fosfatase alcalina também teve redução (23%) na sua produção. Além disso, foi observada redução no perfil lipídico para o LDL (15%). Ainda, os níveis de TGO e TGP tiveram redução significativa de 42% e 25%, respectivamente. Os níveis de glicose sanguínea após o tratamento reduziram margens de 22%. Conclusão: Em conclusão, a cerveja enriquecida com B. dracunculifolia oferece um valor terapêutico promissor na prevenção do diabetes e do perfil dislipidêmico.

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Section: Resultsunclassified

Propriedades antidiabéticas de cerveja enriquecida com Baccharis dracunculifolia

Silva¹,

Silva²,

Malfatti³

et al. 2022

RSD

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“…This is in line with Nurhaliza's research (in Munira et al, 2020) who added that the largest class of compounds found in Chinese betel nut are flavonoids. According to Angelina et (in Momin & Yeligar, 2019), the Chinese betel plant (Peperomia pellucida L.) contains alkaloids, flavonoids, saponins, tannins and triterpenoids (Slavova & Karanasios, 2018). Apart from these ingredients, Chinese betel (Peperomia pellucida L.) also contains other chemical compounds that have been studied previously, namely essential oil compounds, especially carotol dillapiole , βcarophyllene (Patra et al, 2020).…”

Section: Chinese Betel Nut (Peperomia Pellucida L) Phytochemicalsmentioning

confidence: 99%

Characterization of Alluvial Soil for Growth of Chinese Betel (Peperomia pellucida L.)

Silahooy

2023

IJMABER

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This study aims to determine the characterization of alluvial soil as a place to grow Chinese betel (peperomia pellucida L.) in Ambon city. Parameters studied included morphological characterization of alluvial soil and description of Chinese betel nut (Peperomia pellucid a L.). The results of observations in the field and analysis of soil samples in the laboratory that have been collected are used as material to identify soil morphological characterization. Meanwhile Chinese betel nut (Peperomia pellucid a L.) collected from alluvial soil was selectively explored by exploring the research area using the Cruise Method. Furthermore, a phytochemical test was carried out to determine its phytochemical content. The results showed that the color of the soil and the rusty color of the alluvial soil in Ambon City was generally brown. The alluvial soil structure at the study site has an O horizon with a soil layer thickness of 17 cm, an A horizon with a thickness of 45 cm soil lumpy structure and a Bw horizon with a soil thickness of 30 cm and the C horizon with a thickness of 65 cm is classified as having a globular lumpy soil structure, It has a high clay and silt content. The lower the soil solum, the lower the C-organic content. The soil in Ambon city has moderate fertility. Low base saturation is associated with low C-organic content in the soil. Chinese sirih that grows on alluvial soil types in Ambon City contains several classes of compounds that are beneficial to health like flavonoids, alkaloids, tripenoids, phenolics, tannins and saponins so that they have ethnomedicin effects such as anticancer, antimicrobial, antidiabetic, antihypertensive and antioxidant activities.

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Sub-chronic effects of Baccharis dracunculifolia treatment on biochemical, oxidative, and histopathological parameters in diabetic rats

et al. 2022

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Background: Oxidative stress and the mild inflammatory process present in diabetes play a critical role in the pathogenesis of the disease and its comorbidities. This understanding has opened new avenues and targets for developing improved treatments since the risk factors associated with diabetes may be reduced through non-pharmacological interventions. In this sense, plant extracts could be efficient in preventing or assisting these pathological conditions treatment. Methods: Diabetes mellitus was induced in 24 rats, which were allocated in 4 groups: Control (CT), Control+Baccharis (CT-B), Diabetes (DB), and Diabetes+Baccharis (DB-B). For 28 days, the animals of CT-B and DB-B groups were treated, via gavage, with B. dracunculifolia extract at 50 mg.kg-1. Results: The DB group presented higher values than the DB-B group on parameters such as creatinine (26.42%), urea (31.42%), and triglycerides (60.80%). Creatinine and triglycerides values of DB-B group (0.39±0.01 e 75.0±8.4, receptively) were equivalent to the values of CT group (0.32±0.01 e 71.7±5.4) and of CT-B group (0.39±0.01, and 58.8±4.5). The treatment with B. dracunculifolia improved the levels of fasting glucose and response of glucose tolerance (32%), insulin (52,17%) and lipid peroxidation (liver 33.33%, kidney 38.77%) when compared to the DB group. Conclusions: The phenolic compounds and the anti-inflammatory activity of the extract of Baccharis dracunculifolia may be responsible for the hypoglycemic effect observed in the study.

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The Antidiabetic and Antioxidant Activity of Coccinea Grandis Voigt Stem Extract in Streptozotocin Induced Diabetic Rats

Cited by 5 publications

References 9 publications

Propriedades antidiabéticas de cerveja enriquecida com Baccharis dracunculifolia

Propriedades antidiabéticas de cerveja enriquecida com Baccharis dracunculifolia

Characterization of Alluvial Soil for Growth of Chinese Betel (Peperomia pellucida L.)

Sub-chronic effects of Baccharis dracunculifolia treatment on biochemical, oxidative, and histopathological parameters in diabetic rats

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