The Antibacterial Activity of Satureja khuzestanica Essential Oil Against Clinical Isolates of E. coli

Abstract

Background: In folk medicine, Satureja khuzestanica infusion is prescribed to use before the meals to treat muscle pains, indigestion, cramps, nausea, diarrhea, and infectious diseases, especially bladder infections and inflammations. Objectives: This study aimed to evaluate the antibacterial activity of S. khuzestanica essential oil against clinical isolates of E. coli from urinary tract infections. Materials and Methods:The chemical composition of S. khuzestanica essential oil was determined by gas chromatography (GC) and mass spectrometer (GC-MS) analyses. The antibacterial activity of S. khuzestanica essential oil and carvacrol as its main component was evaluated by disk diffusion and microbroth dilution assays. Then, the synergistic activity of essential oil and carvacrol with gentamicin were determined by checkerboard microtiter assay. Results: The chemical analysis of S. khuzestanica essential oil revealed the presence of carvacrol (94.1%) as its main component. The inhibition zone diameters of S. khuzestanica essential oil and carvacrol dose-dependently increased. The Minimum Inhibitory

The study of formulated Zoush ointment against wound infection and gene expression of virulence factors Pseudomonas aeruginosa

“…Kamdem et al showed that carvacrol had no specific effect on Listeria monocytogenes at 37 °C but was effective at 55 °C [ 46 ]. Mahbubi et al studied the antibacterial properties of S. khuzestaniea essential oil on clinical isolates of Escherichia coli [ 47 ]. Jourabi et al examined the antimicrobial effects of S. khuzestaniea and Z. multiflora with broth microdilution method on E. coli , S. aureus , C. albicans and Aspergillus niger [ 48 ].…”

In-Vitro Antimicrobial Activity and Chemical Composition of Satureja khuzestanica Jamzad Essential Oils Against Multidrug-Resistant Acinetobacter baumannii

“…In this study, the essential oil of S. khuzestanica contained almost 93% carvacrol as the major component. Also other investigators have reported over 90% carvacrol content in the S. khuzestanica essential oils which is collected from different areas of Iran (11,15,24,25). The antimicrobial activity of carvacrol, a phenolic monoterpene has been shown that be related to the presence of a free hydroxyl group and their hydrophobic nature essential for damaging cell membranes (26).…”

“…The antibacterial activity of S. khuzestanica essential oil has been shown against a number of bacteria including Grampositive food pathogens, some members of Enterobacteriaceae, as well as Pseudomonas aeruginosa (13,14). Other recent studies have been shown that carvacrol-rich S. khuzestanica EO has antimicrobial activity against clinical urinary isolates of E. coli, a number of Gram-positive cocci and yeast strains (15,16). Also the effect of S. khuzestanica EO has been shown on the expression of the bap gene which is involved in biofilm formation and bla gene in antibiotic resistant A. baumannii using polymerase chain reaction (17,18).…”

Phytochemical and biological activities of some Iranian medicinal plants

“… 2016 ). Mahboubi and Kazempour ( 2016 ) evaluated in vitro antibacterial activity of S. khuzestanica essential oil, carvacrol and gentamicin and their synergistic effect on E. coli. They found that antibacterial activity of carvacrol was higher than essential oil.…”