The antibacterial activity of bacterial endophytes isolated from Combretum molle

Diale, Mamonokane Olga; Ubomba-Jaswa, Eunice; Serepa-Dlamini, Mahloro Hope

doi:10.5897/ajb2017.16349

Cited by 14 publications

(3 citation statements)

References 27 publications

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“…pneumoniae, Proteus mirabilis, Shigella flexneri , and S. aureus (Beiranvand et al, 2017; Figure 1, 3), whereas Malaysian plants-endophytic B. subtilis possessed antibacterial activity against S. aureus , methicillin resistant S. aureus , and P. aeruginosa (Fikri et al, 2018; Figure 2B). The African Combretum molle -endophytic Bacillus and Lysinibacillus species exhibited antibacterial activity against B. cereus, E. coli, P. aeruginosa , and S. aureus (Diale et al, 2018; Supplementary Table S1).…”

Section: Gram-positive Endophytes Against Human/animal Pathogensmentioning

confidence: 99%

Bioactive Products From Plant-Endophytic Gram-Positive Bacteria

et al. 2019

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Endophytes constitute plant-colonizing microorganisms in a mutualistic symbiosis relationship. They are found in most ecosystems reducing plant crops’ biotic and abiotic stressors by stimulating immune responses, excluding plant pathogens by niche competition, and participating in antioxidant activities and phenylpropanoid metabolism, whose activation produces plant defense, structural support, and survival molecules. In fact, metabolomic studies have demonstrated that endophyte genes associated to specific metabolites are involved in plant growth promotion (PGP) by stimulating plant hormones production such as auxins and gibberellins or as plant protective agents against microbial pathogens, cancer, and insect pests, but eco-friendly and eco-safe. A number of metabolites of Gram-positive endophytes isolated from agriculture, forest, mangrove, and medicinal plants, mainly related to the Firmicutes phyla, possess distinctive biocontrol and plant growth-promoting activities. In general, Actinobacteria and Bacillus endophytes produce aromatic compounds, lipopeptides, plant hormones, polysaccharides, and several enzymes linked to phenylpropanoid metabolism, thus representing high potential for PGP and crop management strategies. Furthermore, Actinobacteria have been shown to produce metabolites with antimicrobial and antitumor activities, useful in agriculture, medicine, and veterinary areas. The great endophytes diversity, their metabolites production, and their adaptation to stress conditions make them a suitable and unlimited source of novel metabolites, whose application could reduce agrochemicals usage in food and drugs production.

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Section: Gram-positive Endophytes Against Human/animal Pathogensmentioning

confidence: 99%

Bioactive Products From Plant-Endophytic Gram-Positive Bacteria

et al. 2019

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“…Bacterial strains of S. aureus (ATCC 25923) and K. pneumoniae (ATCC 13822) were each incubated with and without AuNPs (62.5 μg/mL) at 37 °C for 24 h. Samples were collected from both cultures and processed for SEM analysis by adapting the method by [ 36 ]. In brief, the samples were centrifuged at 1100× g for 10 min, and the supernatant was poured out.…”

Section: Methodsmentioning

confidence: 99%

Facile Green, Room-Temperature Synthesis of Gold Nanoparticles Using Combretum erythrophyllum Leaf Extract: Antibacterial and Cell Viability Studies against Normal and Cancerous Cells

et al. 2021

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We herein report a facile, green, cost-effective, plant-mediated synthesis of gold nanoparticles (AuNPs) for the first time using Combretum erythrophyllum (CE) plant leaves. The synthesis was conducted at room temperature using CE leaf extract serving as a reducing and capping agent. The as-synthesized AuNPs were found to be crystalline, well dispersed, and spherical in shape with an average diameter of 13.20 nm and an excellent stability of over 60 days. The AuNPs showed broad-spectrum antibacterial activities against both pathogenic Gram-positive (Staphylococcus epidermidis (ATCC14990), Staphylococcus aureus (ATCC 25923), Mycobacterium smegmatis (MC 215)) and Gram-negative bacteria (Proteus mirabilis (ATCC 7002), Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATCC 13822), Klebsiella oxytoca (ATCC 8724)), with a minimum inhibition concentration of 62.5 µg/mL. In addition, the as-synthesized AuNPs were highly stable with exceptional cell viability towards normal cells (BHK- 21) and cancerous cancer cell lines (cervical and lung cancer).

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“…In addition, Islam et al [ 79 ] isolated B. thuringiensis with antibacterial activity from several gymnosperms and angiosperms. Similarly, bacterial endophytes isolated from the leaves of Malaysian and African plants with medicinal properties have been reported to be a rich source of antibiotics exhibiting activities against S. aureus, B. cereus, E. coli , and P. aeruginosa [ 80 , 81 ].…”

Section: Production Of Secondary Metabolitesmentioning

confidence: 99%

Secondary Metabolites Produced by Plant Growth-Promoting Bacterial Endophytes

Narayanan

Glick

2022

Microorganisms

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There is an increasing interest in the use of beneficial microorganisms as alternatives to chemically synthesized or plant-derived molecules to produce therapeutic agents. Bacterial endophytes are plant-associated microorganisms that can colonize different parts of living plants without causing any diseases. Diverse endophytic bacteria possess the ability to synthesize a wide range of secondary metabolites with unique chemical structures that have been exploited for their anti-microbial, antiviral, anti-cancer, and anti-inflammatory properties. Additionally, production of these bioactive compounds can also benefit the host plant as they may play a significant role in a plant’s interaction with the environment for adaptation and defense. As a result of their significant impact as curative compounds or as precursors to produce new drugs, the biotechnological possibilities of secondary metabolites derived from endophytic bacteria are immense.

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The antibacterial activity of bacterial endophytes isolated from Combretum molle

Cited by 14 publications

References 27 publications

Bioactive Products From Plant-Endophytic Gram-Positive Bacteria

Bioactive Products From Plant-Endophytic Gram-Positive Bacteria

Facile Green, Room-Temperature Synthesis of Gold Nanoparticles Using Combretum erythrophyllum Leaf Extract: Antibacterial and Cell Viability Studies against Normal and Cancerous Cells

Secondary Metabolites Produced by Plant Growth-Promoting Bacterial Endophytes

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