“…Lower Zn 2+ fractions are distributed across various tissues, including the kidney, prostate, liver, gastrointestinal tract, skin, lung, brain, heart, and pancreas [5][6][7][8][9] . Within these organs, intracellular Zn 2+ serves as an essential cofactor for the catalytic activity and structural integrity of over 300 proteins, including those involved in synthesis of macromolecules and cell division [10][11][12][13] .…”