The Anti-HIV Activity and Mechanisms of Action of Pure Compounds Isolated fromRosa damascena

Mahmood, Naheed; Piacente, Sonia; Pìzza, Cosimo; Burke, Andrew; Khan, Adil I.; Hay, Alan J.

doi:10.1006/bbrc.1996.1759

Cited by 165 publications

(89 citation statements)

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“…Some rose preparations are used medicinally as tonics, mild laxatives and in treatment of sore throat, enlarged tonsils, cardiac troubles, eye disease as well as gall stones (Verma et al, 2011a). In addition, anti-HIV (Mahmood et al, 1996), antibacterial and analgesic (Basim and Basim, 2003), antispasmodic and hypnotic activities (Boskabady et al, 2006), antitussive, anti-inflammatory (Köse et al, 2007) and anxiolytic-like (Almeida et al, 2004) effects of rose extract/isolates have been reported. Furthermore, rose oil aroma has been identified to have positive effects on learning and memory (Köse et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Determination of volatile compounds of the first rose oil and the first rose water by HS-SPME/GC/MS techniques

Koksal¹,

Saribas²,

Kafkas³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

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Background: Rose water and rose oil are used in the perfume, cosmetic, pharmaceutical and food industries. The determination of volatile compounds in rose oil and rose water obtained from oil-bearing rose is highly important in terms of availability in the industry and in human health. Materials and Methods: Twenty four and twenty six volatile compounds were determined in the first rose oil and in the first rose water. Thus, in this study, volatile compounds in the first rose oil and first rose water have been determined by HS-SPME/GC/MS (Headspace-Solid Phase Micro Extraction/Gas Chromatography Mass Spectrometry) techniques which were not published previously for determining volatile compounds in rose oil and rose water. Results: Twenty four and twenty six volatile compounds were found in the first rose oil and in the first rose water, respectively. It was further discovered that both first rose oil and first rose water are rich in oxygenated monoterpenes and sesquiterpenes, with a third group of volatile compounds known as aliphatic hydrocarbons being found only in first rose oil. Citronellol contents of the first rose oil and rose water were found to be 43.40% and 40.13% respectively, whereas geraniol contents were 11.81% and 15.97%, respectively. Conclusion: These findings suggest that HS-SPME/GC/MS is a suitable technique for the determination of volatile compounds of rose oil and rose water.

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Section: Introductionmentioning

confidence: 99%

Determination of volatile compounds of the first rose oil and the first rose water by HS-SPME/GC/MS techniques

Koksal¹,

Saribas²,

Kafkas³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

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“…Quercitin seems to exert antibacterial activity against almost all the strains of bacteria known to cause respiratory, gastrointestinal, skin and urinary disorders (Rigano et al, 2007). Quercitin appeared active against different viruses (Kaul et al, 1985) including HIV (Mahmood et al, 1996), probably due to inhibition of reverse transcriptase (Nakane and Ono 1990).…”

Section: Resultsmentioning

confidence: 99%

Antibacterial activity of Glycyrrhiza glabra roots against certain gram-positive and gram-negative bacterial strains

Gupta

Maheshwari

Khandelwal

2013

JANS

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Abstract:The present study aimed to evaluate the antibacterial potency of grinded crude material (root of Glycyrrhiza glabra) against some gram-positive and gram-negative bacterial strains. Two solvents (methanol and acetone) were used to extract the phytochemicals from the test material. Four different concentrations (100%, 75%, 50% and 25%) of methanolic and acetonic extract were used to investigate the inhibiting properties against Salmonella typhi, Escherichia.coli, Vibrio cholerae, Staphylococcus aureus, Bacillus cereus and Bacillus subtilis strains. Among methanol and acetone extracts, later exhibited low antibacterial activity. The 100% (w/v) concentration of both extracts showed maximum inhibition against B. subtilis followed by E. coli, S. aureus, B. cereus, S. typhi and V. Cholerae. Maximum activity in acetonic extract was obtained against B. cereus followed by S. typhi, E. coli, V. cholerae and S .aureus and minimum in B. subtilis. A reverse pattern of inhibition activity was found in both extacts (methanolic and acetonic) against B. subtilis. Maximum activity was found in methanolic extract against B. subtilis (18.6 mm) but it was only 14.3 mm against this strain in acetonic extract. The antibacterial activity of the crude samples corresponded to that of concentration. Hence there was positive correlation of antibacterial activity with the test material.

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“…In addition to its perfuming effects, it was reported that the rose oil, rose flower extracts possessed a wide range of health beneficial activities, such as antibacterial 12,46,47 , antioxidant 13,14,48 , anti-infective and antiinflammatory properties 12,49 , anti-convulsant 50 and anti-HIV 11 . The extract of R. damascena induces the neurite outgrowth and inhibits the A β (25-35)-induce atrophy 51 .…”

Section: Rose Product and Its Usesmentioning

confidence: 99%

“…This plant was originally brought to Europe from Damascus that is why it is called Damask rose 9,10 . Besides its application in aromatic industries, some valuable characteristics of Damask rose oil such as anti-HIV 11 antibacterial 12 and antioxidant 13,14 activities have been reported recently. The worldwide demand for high quality rose oil is expected to increase in future.…”

Section: Introductionmentioning

confidence: 99%

Evaluation, Genetic Diversity, Recent Development of Distillation Method, Challenges and Opportunities ofRosa damascena: A Review

Pal

2013

Journal of Essential Oil Bearing Plants

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Rosa damascenaMill that is one of the important species of Rosa is used for essential oil production. It is a tetraploid rose that belongs to Damask group of roses. It is generally thought that the R. damascena originated in the Neo-lithic period, in South Anatolia, as a hybridization of R. gallica and R. phoenicea. Nevertheless, the origin of R. damascena is a bone of contention throughout the world. So far, 400 volatile substances have been identified in rose oil. Besides its application in aromatic and food industries, some valuable characteristics of Damask rose oil such as anti -HIV, antibacterial and antioxidant activities have been established during last two decades. The demand of rose oil in international market is increasing, but the area of production is stagnant. Thus, there is a pressing need to extend the cultivation of R. damascena to larger area and to improve its production technology. Rosa damascena possesses vast diversity in plant habit and flower characteristics. Over all, the research publication on this crop is scarce compared to other crops. Hence, this review will provide the valuable information for further research and understanding of the crop and its value as an economical crop.

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The Anti-HIV Activity and Mechanisms of Action of Pure Compounds Isolated fromRosa damascena

Cited by 165 publications

References 0 publications

Determination of volatile compounds of the first rose oil and the first rose water by HS-SPME/GC/MS techniques

Determination of volatile compounds of the first rose oil and the first rose water by HS-SPME/GC/MS techniques

Antibacterial activity of Glycyrrhiza glabra roots against certain gram-positive and gram-negative bacterial strains

Evaluation, Genetic Diversity, Recent Development of Distillation Method, Challenges and Opportunities ofRosa damascena: A Review

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