The anti‑fatigue activities of Tuber melanosporum in a mouse model

Jiang, Xue; Chu, Qiubo; Li, Lanzhou; Qin, Luyao; Hao, Jie; Kou, Ling; Wang, Di

doi:10.3892/etm.2018.5793

Cited by 16 publications

(17 citation statements)

References 38 publications

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“… Antihyperglycemic, Antioxidant, Antibacterial and hypoglycemic [ 219 ] 36 Tricholoma giganteum Matsutake India Apoptogenic, Antioxidant, Anticancer and hepatoprotective [ 220 , 221 ] 37 Tricholoma matsutake Matsutake Asia, Europe North America Japan, Korea, and China Immunostimulator, Antioxidant, Antitumor and Anti-microbial [ 222 , 223 ] 38 Tremella fuciformis Snow mushroom/Silver Ear mushroom/ White jelly fungus Asia, America, sub-Saharan Africa, southern and eastern Asia, Australia, and Pacific Islands. Hypoglycemic effect, Hypocholesteromic effect, Antioxidant activity, and Anti-inflammatory [ 224 , 225 ] 39 Tuber aestivum Burgundy truffle Europe Antioxidant, Anti-inflammatory Antiviral, Antimicrobial, Hepatoprotective and Anti-mutagenic [ 226 , 227 ] 40 Tuber melanosporum Black truffle Spain, France and Italy Anti-fatigue, Antitumor, Antioxidant and neurotropic [ 77 , 228 ] 41 Volvariella volvacea Paddy straw mushroom Malaysia, China and India Anti-tumor and Immunomodulatory [ 229 , 230 ] …”

Section: Edible Mushroomsmentioning

confidence: 99%

A review of the therapeutic and biological effects of edible and wild mushrooms

Anusiya¹,

Prabu²,

Yamini³

et al. 2021

Bioengineered

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Throughout history, mushrooms have occupied an inseparable part of the diet in many countries. Mushrooms are considered a rich source of phytonutrients such as polysaccharides, dietary fibers, and other micronutrients, in addition to various essential amino acids, which are building blocks of vital proteins. In general, mushrooms offer a wide range of health benefits with a large spectrum of pharmacological properties, including antidiabetic, antioxidative, antiviral, antibacterial, osteoprotective, nephroprotective, hepatoprotective, etc. Both wild edible and medicinal mushrooms possess strong therapeutic and biological activities, which are evident from their in vivo and in vitro assays. The multifunctional activities of the mushroom extracts and the targeted potential of each of the compounds in the extracts have a broad range of applications, especially in the healing and repair of various organs and cells in humans. Owing to the presence of the aforementioned properties and rich phytocomposition, mushrooms are being used in the production of nutraceuticals and pharmaceuticals. This review aims to provide a clear insight on the commercially cultivated, wild edible, and medicinal mushrooms with comprehensive information on their phytochemical constituents and properties as part of food and medicine for futuristic exploitation. Future outlook and prospective challenges associated with the cultivation and processing of these medicinal mushrooms as functional foods are also discussed.

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Section: Edible Mushroomsmentioning

confidence: 99%

A review of the therapeutic and biological effects of edible and wild mushrooms

Anusiya¹,

Prabu²,

Yamini³

et al. 2021

Bioengineered

View full text Add to dashboard Cite

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“…Although many aspects of fatigue have been studied for a long time, no appropriate method has been established for the optimal and objective assessment of fatigue. The forced swim test is often used in mouse studies to measure fatigue [14][15][16]. In this study, we hypothesized that IR and RI are the peptides with the highest antioxidant activity in FMDP.…”

Section: Discussionmentioning

confidence: 96%

Effects of Fish Meat-derived Peptide and Dipeptides on Dexamethasone-induced Fatigue in Mice

Iwasaki¹,

Sakai²,

Asami³

et al. 2019

JFNR

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In patients with inflammatory diseases, exogenous glucocorticoids have become the most common cause of drug-induced muscle wasting. In this study, we showed that isoleucine-arginine (IR) and arginineisoleucine (RI) are the main dipeptides with antioxidant activity in fish meat-derived peptide extract (FMDP). To investigate the anti-fatigue effect of FMDP and the two dipeptides (IR or RI), dexamethasone (DEX)-treated mice performed a weighted forced swimming test. Despite no change in body weight, the shortened swim time after DEX administration returned to baseline levels following the administration of FMDP, IR, and RI. However, the swim time of naive mice cannot be extended with the administration of FMDP, IR, or RI. Our data suggest that FMDP, IR, and RI may have beneficial effects on DEX-induced fatigue in mice. Nevertheless, further research is required to determine the mechanism through which FMDP reduces fatigue.

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“…Nowadays, weight-loaded forced swimming test is widely applied to evaluate anti-fatigue effect and endurance capacity for exercise performance in mice [8]. In this study, we first investigated the influence of PC on the body weight and physiological status of mice.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of anti-fatigue property of Porphyridium cruentum in mice

Huang¹,

Wang²,

Li³

et al. 2021

Trop. J. Pharm Res

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Purpose: To evaluate the potential effects of Porphyridium cruentum (PC) on fatigue induced by forced swimming test in mice. Methods: Mice were randomly divided into normal control group (NC, i.e., untreated non-swimming); model control group (MC, untreated swimming); Spirulina treated group (SP, 800 mg/kg); PC-treated groups (50, 100, and 200 mg/kg), respectively. After intragastric administration for 14 consecutive days, a weight-bearing swimming experiment was conducted for the mice, and the biochemical indicators related to fatigue were examined, including exhaustive swimming time, glucose levels (Glu), hepatic glycogen contents (HG), muscle glycogen contents (MG), glutathione peroxidase activities (GSH-Px), creatine kinase (CK), malondialdehyde (MDA), urea nitrogen levels (SUN), lactate dehydrogenase activities (LDH), lactic acid (LA) as well as superoxide dismutase (SOD). Results: PC significantly prolonged the swimming endurance time compared to MC. After PC treatment, Glu, HG and MG were effectively increased dose-dependently, SUN, LA, LDH and CK levels in serum were significantly reduced. Moreover, PC treatment elevated the bioactivities of two antioxidant enzymes, namely, GSH-Px and SOD, while MDA content decreased when compared to MC group. Conclusion: These results indicate that PC exhibits strong anti-fatigue effect. Thus, PC may be suitable for incorporation in functional food to counter fatigue.

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The anti‑fatigue activities of Tuber melanosporum in a mouse model

Cited by 16 publications

References 38 publications

A review of the therapeutic and biological effects of edible and wild mushrooms

A review of the therapeutic and biological effects of edible and wild mushrooms

Effects of Fish Meat-derived Peptide and Dipeptides on Dexamethasone-induced Fatigue in Mice

Evaluation of anti-fatigue property of Porphyridium cruentum in mice

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